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Evidence-based GLP-1 & peptide discussion since 2023
ForumsPublic SquareIs there a ceiling effect for GLP-1-mediated weight loss? — looking for input Page 2

Is there a ceiling effect for GLP-1-mediated weight loss? — looking for input

VanRx_Mike Thu, May 9, 2024 at 4:23 PM 17 replies 2,124 viewsPage 2 of 4
julia.endo
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May 9, 2024 at 7:13 PM#6

Congrats VanRx_Mike!! Keep going — you're doing incredible. 🎉

Last edited: May 10, 2024 at 1:13 AM
4 14anna.melb_AU, mark_tokyo, hans_munich and 1 other
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VendorMark
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May 9, 2024 at 7:30 PM#7

Clinical perspective on Is there a ceiling effect for:

I have managed ~150 patients on GLP-1 therapy and this topic comes up frequently. What the data shows — and what I see in practice — is that proper titration prevents most adverse events.

For this specific question, I would recommend: reviewing the relevant clinical guidelines.

21 3KristenIndy, MarkLI_maint, Dr.PeteFamMed and 18 others
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TrialTracker_MD
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May 9, 2024 at 7:47 PM#8

100%. My provider said the same thing about Is there a ceiling.

3 0maya_sedona, stefan_berlin, Dr.EM_Chicago
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COA_Karl
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May 9, 2024 at 8:04 PM#9

Reading this thread on Is there a ceiling effect hits close to home. Dad of 2 checking in — I started at 285 lbs and felt like I would tried everything.

11 months on tirz and I am a different person. Not just the 60 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about Is there a ceiling — take the leap. It was the best health decision I have ever made. ❤️

25 0tommy_boulder, hyun_seoul, jim_asheville and 22 others
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FranDenver
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Denver, CO
May 9, 2024 at 8:21 PM#10
julia.endo said:
Keep going — you're doing incredible

This is exactly right. julia.endo articulated what I have been trying to explain to my doctor for months. The Is there a ceiling effect aspect is the most important factor.

Last edited: May 10, 2024 at 2:21 AM
32 15GenomicsKate, Dr.ObesityMed, HealthEcon_DC and 29 others
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