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ForumsPublic SquareComparative pharmacokinetics: semaglutide vs tirzepatide vs retatrutide — need advice Page 2

Comparative pharmacokinetics: semaglutide vs tirzepatide vs retatrutide — need advice

emily_PDX Fri, Apr 26, 2024 at 4:07 PM 36 replies 2,470 viewsPage 2 of 8
sarah.morrison
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Apr 26, 2024 at 6:57 PM#6
mike.trainer_LA said:
I have been dealing with this for over a year now, and what I have found is that individual response

Gonna push back on this one. Comparative pharmacokinetics is not that straightforward in my experience. I have been on this for 12 months and the reality is messier than the trials suggest.

Don't get me wrong — the medication works. But cost accessibility is a real barrier. We should be honest about that.

Last edited: Apr 26, 2024 at 7:57 PM
40 11josh_phd_bmore, roxy_nash, tony_orlando and 37 others
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jason_paloalto
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Apr 26, 2024 at 7:14 PM#7

Adding my data to this Comparative discussion:

MetricBaselineMonth 5Month 6
Weight268 lbs243 lbs203 lbs
A1C7.2%6.0%5.2%
hsCRP7.04.01.0

Protocol: Semaglutide 1.7mg/wk, resistance training 3x/wk, protein 1.5g/kg/day.

Last edited: Apr 27, 2024 at 12:14 AM
28 8Dr.PathRoch, mona_PHX, andrew_nyc and 25 others
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sarah_nash92
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Apr 26, 2024 at 7:31 PM#8

julia.endo — wow. This community is amazing.

32 0ZaraB_AL, JakeSmashed95, NauseaFreeNow and 29 others
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MASHdoc_SA
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Apr 26, 2024 at 7:48 PM#9

Slightly tangential to Comparative but TomFromTexas reminded me — what is the latest on the oral formulations?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

12 14LabKate, kate.chem, DataDave and 9 others
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mike_mod
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Apr 26, 2024 at 8:05 PM#10

Moderator note: Please keep vendor-specific discussions in the Vendor Reviews section.

I have cleaned up a few off-topic posts. 👍

46 17PurityPaulOR, MaxMetOK, MounjBrad and 43 others
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