Following this thread closely. Comparative is something I'm actively working through.
ZaraB_AL said:Dad of 2 checking in — I started at 273 lbs and felt like I would tried everything
I respect ZaraB_AL perspective but I think this oversimplifies things a bit. Re: Comparative pharmacokinetics — the subgroup analyses show meaningful heterogeneity.
I am not saying ZaraB_AL wrong entirely — just that the picture is more nuanced than a blanket statement. The SURMOUNT data specifically shows baseline BMI-dependent responses.
Reading this thread on Comparative hits close to home. Night shift nurse — I started at 299 lbs and felt like I would tried everything.
15 months on tirz and I am a different person. Not just the 74 lbs lost — my energy, my mood, my relationship with food. All transformed.
If you are on the fence about Comparative — take the leap. It was the best health decision I have ever made. ❤️
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stefan_berlin — that is really helpful context on Comparative. Follow-up question: did you change anything about your diet at the same time?
I am in a similar situation (month 2) and trying to set realistic expectations.