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Evidence-based GLP-1 & peptide discussion since 2023
ForumsCardiovascular OutcomesHas anyone dealt with tirzepatide cardiovascular safety? Page 5

Has anyone dealt with tirzepatide cardiovascular safety?

carlos_SATX Mon, Jun 23, 2025 at 10:20 PM 41 replies 1,657 viewsPage 5 of 9
SarahChen_PharmD
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Jun 24, 2025 at 5:25 AM#21

Want to share my personal experience related to Has anyone dealt with since I think it might help others in a similar situation.

I started my GLP-1 journey in October 2024 at 248 lbs with prediabetes and hypertension. My endocrinologist prescribed semaglutide 0.25mg to start.

Now, 12 months later: I am down 83 lbs, my labs have normalized, and I am off 2 of my 3 medications. The Has anyone dealt aspect specifically was something that made a big difference in my journey.

This community helped me every step of the way.

22 16Dr.ObesityLA, NurseKim_ATL, paul_denver and 19 others
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mike_mod
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Jun 24, 2025 at 5:42 AM#22

Moderator note: This thread has been getting great engagement. Please remember to cite sources when making clinical claims.

No issues to report — carry on. 👍

Last edited: Jun 24, 2025 at 7:42 AM
47 6TomTeleRx, DoseLogDan, SleepFixSam and 44 others
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Dr.NateNeph
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Jun 24, 2025 at 5:59 AM#23

Adding my data to this Has anyone dealt with discussion:

MetricBaselineMonth 5Month 8
Weight250 lbs220 lbs215 lbs
A1C6.4%6.0%5.4%
hsCRP4.04.00.8

Protocol: Semaglutide 1.7mg/wk, resistance training 3x/wk, protein 1.2g/kg/day.

Last edited: Jun 24, 2025 at 7:59 AM
28 18SteveThurs, B12Beth, RickReta_CO and 25 others
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wanda_boise
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Aug 2024
Boise, ID
Jun 24, 2025 at 6:16 AM#24

mike_mealprep — wow. I've been looking for this exact info for weeks.

11 10nick_SD_fit, ben_calgary, patPC_UT and 8 others
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FranDenver
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Oct 2024
Denver, CO
Jun 24, 2025 at 6:33 AM#25
Dr.DermMIA said:
Has anyone dealt with is exactly what I've been researching

This is exactly right. Dr.DermMIA articulated what I have been trying to explain to my doctor for months. The Has anyone dealt with aspect is the most important factor.

42 21GenomicsKate, Dr.ObesityMed, HealthEcon_DC and 39 others
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