JessicaH_TX said:Switching from sema to tirz and WOW is not that straightforward in my experience
This is exactly right. JessicaH_TX articulated what I have been trying to explain to my friends for months. The Switching from sema to aspect is what made the difference for me.
Reading this thread on Switching from sema to hits close to home. Dad of 2 checking in — I started at 269 lbs and felt like I would tried everything.
15 months on tirz and I am a different person. Not just the 44 lbs lost — my energy, my mood, my relationship with food. All transformed.
If you are on the fence about Switching from sema — take the leap. It was the best health decision I have ever made. ❤️
Dr.RaviCardio — that is really helpful context on Switching from sema to. Follow-up question: how long did you wait before increasing your dose?
I am in a similar situation (week 4) and trying to set realistic expectations.
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View ResultsTo answer LarryQC_SD's question specifically:
From a clinical standpoint, Switching from sema to tirz is a reasonable concern that deserves a thorough answer.
The short answer: the evidence supports this approach for most patients.
The longer answer involves reviewing the specific clinical trial data relevant to your question, which I am happy to elaborate on if helpful.