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Evidence-based GLP-1 & peptide discussion since 2023
ForumsPublic SquareAlcohol metabolism changes on semaglutide — anyone have experience? Page 2

Alcohol metabolism changes on semaglutide — anyone have experience?

MarkLI_maint Mon, Feb 19, 2024 at 6:00 PM 13 replies 2,158 viewsPage 2 of 3
labquiet_amy
Senior Member
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Mar 2024
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Feb 19, 2024 at 8:50 PM#6
PharmD_Rodriguez said:
Short answer: talk to your prescriber first

Gonna push back on this one. Alcohol metabolism changes on is not that straightforward in my experience. I have been on this for 18 months and the reality is messier than the trials suggest.

Don't get me wrong — the medication works. But adherence is harder than people admit. We should be honest about that.

10 17TrialNerd_Beth, HPLC_Greg, LibrarianMeg and 7 others
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dan_philly
Member
456
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Jul 2024
Philadelphia, PA
Feb 19, 2024 at 9:07 PM#7

Adding my data to this Alcohol metabolism discussion:

MetricBaselineMonth 3Month 8
Weight246 lbs241 lbs201 lbs
A1C7.0%5.8%5.4%
hsCRP5.02.01.2

Protocol: Semaglutide 2.4mg/wk, resistance training 3x/wk, protein 1.3g/kg/day.

Last edited: Feb 20, 2024 at 12:07 AM
7 10AmyNC_wife, SkepticalSean, Dr.CardioMD and 4 others
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newstart_MO
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Feb 2026
Springfield, MO
Feb 19, 2024 at 9:24 PM#8

chris_chi24 — wow. I've been looking for this exact info for weeks.

Last edited: Feb 20, 2024 at 3:24 AM
13 3HPLC_Greg, LibrarianMeg, bri_stats and 10 others
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maria_elpaso
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Sep 2024
El Paso, TX
Feb 19, 2024 at 9:41 PM#9

Slightly tangential to Alcohol metabolism but tampaLisa73 reminded me — has anyone else noticed changes in their alcohol tolerance?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

Last edited: Feb 20, 2024 at 3:41 AM
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mike_mod
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Feb 19, 2024 at 9:58 PM#10

Moderator note: This thread has been getting great engagement. Please remember to cite sources when making clinical claims.

No issues to report — carry on. 👍

28 9PurityPaulOR, MaxMetOK, MounjBrad and 25 others
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