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ForumsTirzepatide (Mounjaro / Zepbound)5mg → 10mg → 15mg titration — March 2026 Page 5

5mg → 10mg → 15mg titration — March 2026

BiostatsBrad Sun, Mar 9, 2025 at 8:46 PM 49 replies 2,557 viewsPage 5 of 10
mona_PHX
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Mar 10, 2025 at 3:51 AM#21

labquiet_amy — that is really helpful context on 5mg → 10mg → 15mg. Follow-up question: did you experience any side effects during this phase?

I am in a similar situation (about to start) and trying to set realistic expectations.

39 20RetaRick_CA, JenPlateau, SallyK_inj and 36 others
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AmyNC_wife
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Jun 2024
North Carolina
Mar 10, 2025 at 4:08 AM#22

Want to share my personal experience related to 5mg → 10mg → 15mg titration since I think it might help others in a similar situation.

I started my GLP-1 journey in March 2025 at 248 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.

Now, 18 months later: I am down 53 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The 5mg → 10mg → 15mg aspect specifically was something that made a big difference in my journey.

This forum was my go-to resource throughout.

Last edited: Mar 10, 2025 at 5:08 AM
11 16julia.endo, JessicaM_2024, TomFromTexas and 8 others
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emma_london
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Oct 2024
London, UK
Mar 10, 2025 at 4:25 AM#23

mona_PHX — that is really helpful context on 5mg → 10mg → 15mg. Follow-up question: did you change anything about your diet at the same time?

I am in a similar situation (month 2) and trying to set realistic expectations.

1 22TomFromTexas
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BrianDallas92
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Oct 2024
Dallas, TX
Mar 10, 2025 at 4:42 AM#24

Want to share my personal experience related to 5mg → 10mg → 15mg titration since I think it might help others in a similar situation.

I started my GLP-1 journey in October 2024 at 265 lbs with prediabetes and hypertension. My endocrinologist prescribed semaglutide 0.25mg to start.

Now, 10 months later: I am down 60 lbs, my labs have normalized, and I am off 2 of my 3 medications. The 5mg → 10mg → 15mg aspect specifically was something that made a big difference in my journey.

This community helped me every step of the way.

48 10Dr.EndoEP, GraceAZ_72, carl_compliance and 45 others
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traveltech_sara
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Jan 2025
Remote, USA
Mar 10, 2025 at 4:59 AM#25

Just wanted to say — for anyone reading this 5mg → 10mg → 15mg thread who is feeling discouraged: it gets better. The first month are the hardest. Hang in there. 💪

46 24BenResearch_OR, MikeKY_noInsulin, Dr.RaviCardio and 43 others
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