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ForumsLab Results & BiomarkersIGF-1 levels on GLP-1 — growth hormone axis considerations Page 3

IGF-1 levels on GLP-1 — growth hormone axis considerations

EndoResFellow Mon, Feb 23, 2026 at 2:42 PM 16 replies 603 viewsPage 3 of 4
mike_mod
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Feb 23, 2026 at 6:57 PM#11

Moderator note: Please keep vendor-specific discussions in the Vendor Reviews section.

I have cleaned up a few off-topic posts. 👍

Last edited: Feb 23, 2026 at 8:57 PM
45 18PharmHunterJen, TomTeleRx, DoseLogDan and 42 others
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Dr.SportsMedIN
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Feb 23, 2026 at 7:14 PM#12

As a healthcare provider, I want to add some clinical context to this discussion on IGF-1 levels on GLP-1 growth hormone.

Building on what EndoResFellow said — the evidence base here is well-established. The key publications to reference are from the SELECT program[1].

Key clinical points:

  1. Efficacy is dose-dependent and typically requires 4-5 weeks to reach steady state
  2. Side effect profile is predictable and usually manageable with standard protocols
  3. Monitoring should include baseline labs and follow-up at 3-month intervals
  4. Patient education significantly improves outcomes and adherence

Standard disclaimer: this is educational, not individualized medical advice.

References:
[1] See thread title for relevant study identification.
49 1lisa_labSD, adam_van, Dr.SurgeonPGH and 46 others
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anders_CPH
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Feb 23, 2026 at 7:31 PM#13
mike_mod said:
I have cleaned up a few off-topic posts

Gonna push back on this one. IGF-1 levels on GLP-1 growth is not that straightforward in my experience. I have been on this for 18 months and the reality is messier than the trials suggest.

Don't get me wrong — the medication works. But adherence is harder than people admit. We should be honest about that.

13 24AussieAnna, BethLabQueen, ChrisMacros and 10 others
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amy_econ_NJ
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Feb 23, 2026 at 7:48 PM#14

Want to share my personal experience related to IGF-1 levels on GLP-1 growth since I think it might help others in a similar situation.

I started my GLP-1 journey in March 2025 at 255 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.

Now, 18 months later: I am down 75 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The IGF-1 levels on aspect specifically was something that made a big difference in my journey.

This forum was my go-to resource throughout.

48 20gary_naperville, sean_dublin, hannah_MT and 45 others
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DeniseRN_TPA
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Feb 23, 2026 at 8:05 PM#15

Saving this for reference. Quality thread.

35 5Dr.BariatricHTX, LindaRN_retired, tommy_boulder and 32 others
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