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ForumsCardiovascular OutcomesLp(a) on GLP-1 agonists — my results so far

Lp(a) on GLP-1 agonists — my results so far

mike.trainer_LA Tue, Feb 18, 2025 at 9:18 AM 10 replies 1,436 viewsPage 1 of 2
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mike.trainer_LA
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Feb 18, 2025 at 10:43 AM#1

Can I just vent for a second about lp(a) on glp-1 agonists my results?

I know this forum is evidence-based and I love that about it, but sometimes you just need to let it out. I hit another plateau and I am frustrated.

Not looking for a fix necessarily — just solidarity. Anyone else going through this right now?

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LipidDoc_ATL
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Feb 18, 2025 at 11:00 AM#2

Good question. For Lp(a) on GLP-1 agonists my results, here is what the evidence says:

  • The clinical trial data (SURMOUNT program) supports this approach
  • Real-world results from this community generally confirm the trial findings
  • Individual variation is real — give it at least 8 weeks before judging

Happy to go deeper on any of these points if helpful.

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raj_cambridge
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Cambridge, MA
Feb 18, 2025 at 11:17 AM#3
LipidDoc_ATL said:
For Lp(a) on GLP-1 agonists my results, here is what the evidence says:The clinical trial data (SUR

Completely agree with LipidDoc_ATL. I would add that Lp(a) on GLP-1 agonists my also has implications for long-term metabolic health that sometimes get overlooked in these discussions.

In my case, following a similar approach led to significant improvements compared to what I was doing before.

Last edited: Feb 18, 2025 at 12:17 PM
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NicoleRaleigh
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Feb 18, 2025 at 11:34 AM#4

Exactly this. My pharmacist said the same thing about Lp(a) on GLP-1.

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james_edin
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Edinburgh, UK
Feb 18, 2025 at 11:51 AM#5

As a pharmacist, I want to add some clinical context to this discussion on Lp(a) on GLP-1 agonists my results so.

Building on what mike.trainer_LA said — the evidence base here is robust. The key publications to reference are from the SUSTAIN program[1].

Key clinical points:

  1. Efficacy is dose-dependent and typically requires 4-5 weeks to reach steady state
  2. Side effect profile is predictable and usually manageable with standard protocols
  3. Monitoring should include baseline labs and follow-up at 3-month intervals
  4. Patient education significantly improves outcomes and adherence

Standard disclaimer: this is educational, not individualized medical advice.

References:
[1] See thread title for relevant study identification.
Last edited: Feb 18, 2025 at 1:51 PM
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