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Evidence-based GLP-1 & peptide discussion since 2023
ForumsCardiovascular OutcomesHas anyone dealt with apob reduction on tirzepatide? Page 7

Has anyone dealt with apob reduction on tirzepatide?

tampaLisa73 Wed, Jan 29, 2025 at 11:05 AM 41 replies 2,416 viewsPage 7 of 9
Dr.MetabolicMD
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Jan 29, 2025 at 9:00 PM#31

To answer BethLabQueen's question specifically:

From a clinical standpoint, Has anyone dealt with apob is something I discuss with patients regularly.

The short answer: discuss this specific situation with your prescribing provider.

The longer answer involves weighing the risk-benefit ratio for your individual situation, which I am happy to elaborate on if helpful.

16 9SleepDoc_PDX, RegAffairsDC, BiostatsBrad and 13 others
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MarkLI_maint
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Jan 29, 2025 at 9:17 PM#32

HealthEcon_DC — that is really helpful context on Has anyone dealt with. Follow-up question: did you change anything about your diet at the same time?

I am in a similar situation (month 2) and trying to set realistic expectations.

30 8TrialNerd_Beth, HPLC_Greg, LibrarianMeg and 27 others
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tampaLisa73
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Tampa, FL
Jan 29, 2025 at 9:34 PM#33

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Has anyone dealt with.

To answer tampaLisa73: yes, I am on compounded sema from a 503B pharmacy.

Quick update: things are still going well. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

13 12sarah_nash92, FitDadDave, RunnerRach and 10 others
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pete_RVA
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Jan 29, 2025 at 9:51 PM#34

HealthEcon_DC — that is really helpful context on Has anyone dealt with. Follow-up question: did you experience any side effects during this phase?

I am in a similar situation (about to start) and trying to set realistic expectations.

8 9MikeNYC_runner and 5 others
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MikeNYC_runner
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Jan 29, 2025 at 10:08 PM#35

Want to share my personal experience related to Has anyone dealt with apob since I think it might help others in a similar situation.

I started my GLP-1 journey in March 2025 at 269 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.

Now, 12 months later: I am down 74 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The Has anyone dealt aspect specifically was something that made a big difference in my journey.

This forum was my go-to resource throughout.

35 18MASHdoc_SA, GenomicsKate, Dr.ObesityMed and 32 others
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