🍪 CompoundTalk uses cookies to improve your experience, analyze traffic, and personalize content. By continuing to use this site, you agree to our Cookie Policy.
Evidence-based GLP-1 & peptide discussion since 2023
ForumsCardiovascular OutcomesAnti-thrombotic properties of GLP-1 receptor activation — looking for input Page 2

Anti-thrombotic properties of GLP-1 receptor activation — looking for input

robert_kc Sun, Jan 19, 2025 at 7:30 AM 26 replies 1,964 viewsPage 2 of 6
pam_columbus
Member
312
1,345
Aug 2024
Columbus, OH
Jan 19, 2025 at 10:20 AM#6

Subscribing to this thread. Anti-thrombotic is exactly what I've been researching. 🙏

17 17kevin_tulsa, Dr.PainCLE, mike_mealprep and 14 others
Reply Quote Save Share Report
LipidDoc_ATL
Senior Member
1,123
5,678
Apr 2024
Atlanta, GA
Jan 19, 2025 at 10:37 AM#7

As a pharmacist, I want to add some clinical context to this discussion on Anti-thrombotic properties of GLP-1.

Building on what quinn_sf said — the evidence base here is robust. The key publications to reference are from the SUSTAIN program[1].

Key clinical points:

  1. Efficacy is dose-dependent and typically requires 4-5 weeks to reach steady state
  2. Side effect profile is predictable and usually manageable with standard protocols
  3. Monitoring should include baseline labs and follow-up at 3-month intervals
  4. Patient education significantly improves outcomes and adherence

Standard disclaimer: this is educational, not individualized medical advice.

References:
[1] See thread title for relevant study identification.
20 8traveltech_sara, AttorneyGrant, DebRD_ATL and 17 others
Reply Quote Save Share Report
hyun_seoul
Member
345
1,456
Jul 2024
Seoul, KR
Jan 19, 2025 at 10:54 AM#8

Reading this thread on Anti-thrombotic hits close to home. Dad of 2 checking in — I started at 273 lbs and felt like I would tried everything.

9 months on tirz and I am a different person. Not just the 48 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about Anti-thrombotic — take the leap. It was the best health decision I have ever made. ❤️

Last edited: Jan 19, 2025 at 2:54 PM
46 16MASHdoc_SA, GenomicsKate, Dr.ObesityMed and 43 others
Reply Quote Save Share Report

Janoshik Analytical — Independent Testing

Trusted third-party HPLC & mass spectrometry analysis. Verify peptide purity with the lab the community relies on. Independent. Accurate. Transparent.

Verify Your Peptides
pete_RVA
Member
178
890
Dec 2024
Richmond, VA
Jan 19, 2025 at 11:11 AM#9

SarahChen_PharmD — that is really helpful context on Anti-thrombotic. Follow-up question: how long did you wait before increasing your dose?

I am in a similar situation (week 4) and trying to set realistic expectations.

Last edited: Jan 19, 2025 at 4:11 PM
12 11MikeNYC_runner and 9 others
Reply Quote Save Share Report
julia.endo
Senior Member
1,890
9,012
Feb 2024
Cincinnati, OH
Jan 19, 2025 at 11:28 AM#10

To answer hyun_seoul's question specifically:

From a clinical standpoint, Anti-thrombotic properties of is a reasonable concern that deserves a thorough answer.

The short answer: the evidence supports this approach for most patients.

The longer answer involves reviewing the specific clinical trial data relevant to your question, which I am happy to elaborate on if helpful.

49 9chris_chi24, tampaLisa73, KarenAZ_mom and 46 others
Reply Quote Save Share Report

Similar Threads

SELECT trial: 20% MACE reduction — mechanistic deep dive7 replies
Semaglutide cardiovascular benefit independent of weight loss11 replies
STEP-HFpEF: semaglutide in heart failure with preserved EF15 replies
GLP-1 and arterial inflammation — hsCRP and IL-6 reduction data18 replies
Lp(a) on GLP-1 agonists — any impact on this risk factor?8 replies
ForumsNewTrendingMembersAccount

Log In

Forgot password?
No account? Register