Want to share my personal experience related to Insulin icodec (Awiqli) need since I think it might help others in a similar situation.

I started my GLP-1 journey in March 2025 at 281 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.

Now, 8 months later: I am down 76 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The Insulin icodec aspect specifically was something that made a big difference in my journey.

This forum was my go-to resource throughout.

MikeNYC_runner — that is really helpful context on Insulin icodec (Awiqli) . Follow-up question: did you change anything about your diet at the same time?

I am in a similar situation (month 2) and trying to set realistic expectations.

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Insulin icodec (Awiqli) .

To answer VendorMark: yes, I am on compounded sema from a 503B pharmacy.

Quick update: things are still going well. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

Just wanted to say — for anyone reading this Insulin icodec thread who is feeling discouraged: it gets better. The first month are the hardest. Hang in there. 💪

100%. My provider said the same thing about Insulin icodec.