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ForumsRetatrutide & Triple AgonistsCompounded retatrutide — will it be available before approval? Page 3

Compounded retatrutide — will it be available before approval?

KevinCompounds Wed, Mar 4, 2026 at 7:36 AM 29 replies 635 viewsPage 3 of 6
DoseLogDan
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Mar 4, 2026 at 11:51 AM#11

+1 to Dr.GastroMayo. Especially the point about "endo perspective but I think this oversi..." — I have seen the same in my own experience with Compounded retatrutide .

1 4newstart_MO
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TomFromTexas
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Mar 4, 2026 at 12:08 PM#12

Want to share my personal experience related to Compounded retatrutide will since I think it might help others in a similar situation.

I started my GLP-1 journey in October 2024 at 276 lbs with prediabetes and hypertension. My endocrinologist prescribed semaglutide 0.25mg to start.

Now, 16 months later: I am down 71 lbs, my labs have normalized, and I am off 2 of my 3 medications. The Compounded retatruti aspect specifically was something that made a big difference in my journey.

This community helped me every step of the way.

16 6Dr.NateNeph, PharmD_Rodriguez, julia.endo and 13 others
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james_edin
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Mar 4, 2026 at 12:25 PM#13

Dr.RaviCardio — that is really helpful context on Compounded retatrutide . Follow-up question: did you experience any side effects during this phase?

I am in a similar situation (about to start) and trying to set realistic expectations.

Last edited: Mar 4, 2026 at 2:25 PM
34 9tane_welly, Dr.PathRoch, mona_PHX and 31 others
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Dr.MetabolicMD
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Mar 4, 2026 at 12:42 PM#14

To answer TomFromTexas's question specifically:

From a clinical standpoint, Compounded retatrutide will is something I discuss with patients regularly.

The short answer: discuss this specific situation with your prescribing provider.

The longer answer involves weighing the risk-benefit ratio for your individual situation, which I am happy to elaborate on if helpful.

45 7Dr.ObesityMed, HealthEcon_DC, PedsEndoPhilly and 42 others
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Dr.RheumBOS
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Mar 4, 2026 at 12:59 PM#15

Saving this for reference. Quality thread.

Last edited: Mar 4, 2026 at 6:59 PM
16 20Dr.PulmRoch, maya_sedona, stefan_berlin and 13 others
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