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ForumsRetatrutide & Triple AgonistsCompounded retatrutide — will it be available before approval? Page 5

Compounded retatrutide — will it be available before approval?

KevinCompounds Wed, Mar 4, 2026 at 7:36 AM 29 replies 635 viewsPage 5 of 6
lisa_labSD
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Mar 4, 2026 at 2:41 PM#21

Just wanted to say — for anyone reading this Compounded retatruti thread who is feeling discouraged: it gets better. The first few weeks are the hardest. Hang in there. 💪

Last edited: Mar 4, 2026 at 5:41 PM
26 8stefan_berlin, Dr.EM_Chicago, pete_RVA and 23 others
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gary_naperville
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Naperville, IL
Mar 4, 2026 at 2:58 PM#22

Want to share my personal experience related to Compounded retatrutide will since I think it might help others in a similar situation.

I started my GLP-1 journey in March 2025 at 271 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.

Now, 18 months later: I am down 51 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The Compounded retatruti aspect specifically was something that made a big difference in my journey.

This forum was my go-to resource throughout.

29 14DoseLogDan, SleepFixSam, PurityPaulOR and 26 others
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Dr.MetabolicMD
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Mar 4, 2026 at 3:15 PM#23

Clinical perspective on Compounded retatrutide will it be:

I have managed ~150 patients on GLP-1 therapy and this topic comes up frequently. What the data shows — and what I see in practice — is that the medication works best as part of a comprehensive approach.

For this specific question, I would recommend: getting comprehensive baseline labs first.

26 17HealthEcon_DC, PedsEndoPhilly, SleepDoc_PDX and 23 others
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quinn_sf
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Jun 2024
San Francisco, CA
Mar 4, 2026 at 3:32 PM#24

Thank you gary_naperville! This is incredibly helpful. Bookmarking for later. 🙏

Last edited: Mar 4, 2026 at 9:32 PM
18 18andrew_nyc, Dr.EndoEP, GraceAZ_72 and 15 others
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jason_paloalto
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Mar 4, 2026 at 3:49 PM#25

Relevant to Compounded retatrutide will — here is my latest bloodwork comparison:

Key improvements: A1C 7.6% → 5.5%, triglycerides 249 → 119 mg/dL, hsCRP 8.0 → 1.3 mg/L. All on tirzepatide for 17 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

Last edited: Mar 4, 2026 at 8:49 PM
9 9Dr.EndoEP, GraceAZ_72, carl_compliance and 6 others
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