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Evidence-based GLP-1 & peptide discussion since 2023
ForumsLab Results & BiomarkersLipid panel improvements mega-thread — need advice Page 4

Lipid panel improvements mega-thread — need advice

MASHdoc_SA Tue, Jan 20, 2026 at 3:56 AM 23 replies 1,035 viewsPage 4 of 5
MASHdoc_SA
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Jan 20, 2026 at 9:36 AM#16

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Lipid panel improvements.

To answer patPC_UT: yes, I am on compounded sema from a 503B pharmacy.

Quick update: things are still going well. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

12 22TirzTom, TrialTracker_MD, JennaRN and 9 others
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HPLC_Greg
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Jan 20, 2026 at 9:53 AM#17

Relevant to Lipid panel improvements — here is my latest bloodwork comparison:

Key improvements: A1C 7.6% → 5.5%, triglycerides 241 → 111 mg/dL, hsCRP 8.0 → 1.1 mg/L. All on tirzepatide for 9 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

14 2JenPlateau, SallyK_inj, CryptoCarl and 11 others
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stefan_berlin
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Berlin, DE
Jan 20, 2026 at 10:10 AM#18

100%. My provider said the same thing about Lipid panel.

12 10KevinCompounds, TirzTom, TrialTracker_MD and 9 others
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Dr.NutriCornell
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Ithaca, NY
Jan 20, 2026 at 10:27 AM#19

Slightly tangential to Lipid panel improvements but wei_SG reminded me — does anyone have experience combining this with metformin?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

11 11JenMemphis, pat_auckland, Dr.GastroMayo and 8 others
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sarah.morrison
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Jan 20, 2026 at 10:44 AM#20
MASHdoc_SA said:
Thank you all for the thoughtful replies on Lipid panel improvements

This is exactly right. MASHdoc_SA articulated what I have been trying to explain to my doctor for months. The Lipid panel improvements aspect is the most important factor.

23 6kim_atl_prep, sarah_TO, wendy_avl and 20 others
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