Echocardiographic changes on GLP-1 — my results so far

Wanted to share some data with the community since I know we're all about evidence here.

Background: I have been tracking everything meticulously since starting sema 12 months ago. Here's what I have found regarding echocardiographic changes on glp-1 my results.

I'll post my numbers below and would love to see others share theirs too. The more data points we have, the better we can all make informed decisions.

Fair warning — this is a long post. TL;DR at the bottom for those who do not want the full breakdown.

james_edin's experience with Echocardiographic changes resonates deeply with mine. I went through almost the identical process — starting dose, titration timeline, side effects, everything.

The main difference: I started 3 months later. But the overall trajectory has been remarkably similar. Down 46 lbs in 11 months.

One thing I would add that james_edin did not mention: the mental health improvements were just as significant.

Thanks for sharing this, james_edin. A few questions about your Echocardiographic experience:

1. What dose are you currently on?
2. How long before you noticed significant changes?
3. Did your doctor have any specific recommendations about Echocardiograph?

I am in a similar boat and trying to learn from others' experiences before my next appointment.

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Echocardiographic changes.

To answer sarah_TO: I get my labs done through Quest every 3 months.

Quick update: my latest labs came back even better. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

Relevant to Echocardiographic changes on — here is my latest bloodwork comparison:

Key improvements: A1C 8.0% → 5.3%, triglycerides 219 → 119 mg/dL, hsCRP 6.0 → 1.3 mg/L. All on tirzepatide for 11 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.