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Evidence-based GLP-1 & peptide discussion since 2023
ForumsClinical Trials & ResearchSo when is the pill version actually coming? Tired of needles — looking for input Page 2

So when is the pill version actually coming? Tired of needles — looking for input

RegAffairsDC Fri, Sep 26, 2025 at 6:35 PM 12 replies 1,142 viewsPage 2 of 3
HPLC_Greg
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Sep 26, 2025 at 9:25 PM#6
BariatricNurseD said:
Tired of needles looking for input — in my experience this comes down to a few key factors

Gonna push back on this one. So when is the pill version is not that straightforward in my experience. I have been on this for 18 months and the reality is messier than the trials suggest.

Don't get me wrong — the medication works. But adherence is harder than people admit. We should be honest about that.

27 4SallyK_inj, CryptoCarl, MariaRD and 24 others
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dave_SLC
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Salt Lake City, UT
Sep 26, 2025 at 9:42 PM#7

Adding my data to this So when is the pill discussion:

MetricBaselineMonth 5Month 8
Weight262 lbs222 lbs197 lbs
A1C6.6%6.0%5.4%
hsCRP6.04.01.2

Protocol: Semaglutide 1.7mg/wk, resistance training 3x/wk, protein 1.4g/kg/day.

11 14NicoleRaleigh, james_edin, FranDenver and 8 others
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MounjBrad
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Sep 26, 2025 at 9:59 PM#8

PharmD_Rodriguez — wow. I've been looking for this exact info for weeks.

18 24nick_SD_fit, ben_calgary, patPC_UT and 15 others
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BiostatsBrad
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Durham, NC
Sep 26, 2025 at 10:16 PM#9

Slightly tangential to So when is the pill but jason_paloalto reminded me — has anyone else noticed changes in their alcohol tolerance?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

Last edited: Sep 26, 2025 at 11:16 PM
49 7james_edin, FranDenver, Dr.BariatricHTX and 46 others
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mike_mod
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Sep 26, 2025 at 10:33 PM#10

Moderator note: This thread has been getting great engagement. Please remember to cite sources when making clinical claims.

No issues to report — carry on. 👍

14 8PurityPaulOR, MaxMetOK, MounjBrad and 11 others
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