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ForumsCardiovascular OutcomesNNT for MACE prevention — July 2024

NNT for MACE prevention — July 2024

gary_naperville Sat, Sep 21, 2024 at 10:59 AM 36 replies 1,910 viewsPage 1 of 8
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gary_naperville
Member
245
1,123
Oct 2024
Naperville, IL
Sep 21, 2024 at 12:24 PM#1

NNT for MACE prevention July 2024 — I finally have something positive to report and wanted to share.

After 6 months of ups and downs, things are clicking. My latest measurements confirmed what I have been feeling — this is working.

Not trying to brag — I know everyone's journey is different. Just want to put some positive energy out there for anyone who needs it today. ❤️

6 17SleepFixSam, PurityPaulOR, MaxMetOK and 3 others
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Dr.AddMedPHL
Senior Member
1,234
6,234
Mar 2024
Philadelphia, PA
Sep 21, 2024 at 12:41 PM#2

gary_naperville's experience with NNT for MACE prevention resonates deeply with mine. I went through almost the identical process — starting dose, titration timeline, side effects, everything.

The main difference: I had more GI issues initially. But the overall trajectory has been remarkably similar. Down 49 lbs in 14 months.

One thing I would add that gary_naperville did not mention: insurance coverage was a major hurdle.

Last edited: Sep 21, 2024 at 2:41 PM
22 13sarah_nash92, FitDadDave, RunnerRach and 19 others
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tane_welly
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Sep 2024
Wellington, NZ
Sep 21, 2024 at 12:58 PM#3

Thanks for sharing this, gary_naperville. A few questions about your NNT for MACE experience:

  1. What dose are you currently on?
  2. How long before you noticed significant changes?
  3. Did your doctor have any specific recommendations about NNT for MACE?

I am in a similar boat and trying to learn from others' experiences before my next appointment.

Last edited: Sep 21, 2024 at 3:58 PM
23 17DanielChem_CHI, marco_milano, pam_columbus and 20 others
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gary_naperville
Member
245
1,123
Oct 2024
Naperville, IL
Sep 21, 2024 at 1:15 PM#4

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on NNT for MACE prevention .

To answer tane_welly: my doctor and I discussed the options and went with brand.

Quick update: I have noticed more improvement since posting this. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

35 14PharmHunterJen, TomTeleRx, DoseLogDan and 32 others
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Dr.PulmRoch
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Jun 2024
Rochester, MN
Sep 21, 2024 at 1:32 PM#5

Adding my data to this NNT for MACE prevention discussion:

MetricBaselineMonth 5Month 6
Weight272 lbs232 lbs197 lbs
A1C6.6%6.0%5.2%
hsCRP6.04.00.6

Protocol: Semaglutide 1.7mg/wk, resistance training 3x/wk, protein 1.4g/kg/day.

21 8KristenIndy, MarkLI_maint, Dr.PeteFamMed and 18 others
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