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ForumsRetatrutide & Triple AgonistsWill retatrutide be the first to break 25% weight loss in Phase 3? Page 5

Will retatrutide be the first to break 25% weight loss in Phase 3?

Dr.ObesityMed Wed, Feb 11, 2026 at 1:48 AM 23 replies 941 viewsPage 5 of 5
MeganSA_TX
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Feb 11, 2026 at 8:53 AM#21

Reading this thread on Will retatrutide be the hits close to home. Night shift nurse — I started at 271 lbs and felt like I would tried everything.

7 months on tirz and I am a different person. Not just the 46 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about Will retatrutide be — take the leap. It was the best health decision I have ever made. ❤️

10 24PharmD_Rodriguez, julia.endo, JessicaM_2024 and 7 others
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Admin
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Feb 11, 2026 at 9:10 AM#22

Moderator note: Reminder: nothing posted here constitutes medical advice. Consult your healthcare provider.

Tagging this for the weekly digest. 👍

Last edited: Feb 11, 2026 at 1:10 PM
12 8SleepDoc_PDX, RegAffairsDC, BiostatsBrad and 9 others
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quinn_sf
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San Francisco, CA
Feb 11, 2026 at 9:27 AM#23

Relevant to Will retatrutide be the first — here is my latest bloodwork comparison:

Key improvements: A1C 7.2% → 5.3%, triglycerides 243 → 113 mg/dL, hsCRP 6.0 → 1.3 mg/L. All on tirzepatide for 11 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

Last edited: Feb 11, 2026 at 3:27 PM
34 7mona_PHX, andrew_nyc, Dr.EndoEP and 31 others
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raj_cambridge
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Cambridge, MA
Feb 11, 2026 at 9:44 AM#24

Thank you SarahChen_PharmD! This is incredibly helpful. Bookmarking for later. 🙏

10 21PharmHunterJen, TomTeleRx, DoseLogDan and 7 others
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KevinCompounds
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Feb 11, 2026 at 10:01 AM#25

+1 to BiostatsBrad. Especially the point about "Will retatrutide be the is exactly what ..." — I have seen the same in my own experience with Will retatrutide be the.

10 6NurseAsh_DET, BenResearch_OR, MikeKY_noInsulin and 7 others
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