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ForumsRetatrutide & Triple AgonistsTriple agonist side effect profile — what to expect from GCG addition Page 2

Triple agonist side effect profile — what to expect from GCG addition

Dr.GastroMayo Sun, Feb 8, 2026 at 6:24 AM 10 replies 603 viewsPage 2 of 2
TirzTom
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Feb 8, 2026 at 9:14 AM#6

Saving this for reference. Top-tier content.

2 6josh_phd_bmore, roxy_nash
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LarryQC_SD
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Feb 8, 2026 at 9:31 AM#7

Slightly tangential to Triple agonist side but LeilaHI reminded me — what is the latest on the oral formulations?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

Last edited: Feb 8, 2026 at 10:31 AM
30 0paul_denver, TinaHashiRN, robert_kc and 27 others
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JennaRN
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Feb 8, 2026 at 9:48 AM#8

+1 to LeilaHI. Especially the point about "A few questions about your Triple agonis..." — I have seen the same in my own experience with Triple agonist side.

28 16BiostatsBrad, PeptideSynthNJ, Dr.KarenChen and 25 others
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Dr.LeslieOBGYN
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Feb 8, 2026 at 10:05 AM#9

Dr.BariatricHTX — that is really helpful context on Triple agonist side. Follow-up question: how long did you wait before increasing your dose?

I am in a similar situation (week 4) and trying to set realistic expectations.

Last edited: Feb 8, 2026 at 4:05 PM
41 8NicoleRaleigh, james_edin, FranDenver and 38 others
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Dr.ObesityLA
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Feb 8, 2026 at 10:22 AM#10

To answer JennaRN's question specifically:

From a clinical standpoint, Triple agonist side effect is a reasonable concern that deserves a thorough answer.

The short answer: the evidence supports this approach for most patients.

The longer answer involves reviewing the specific clinical trial data relevant to your question, which I am happy to elaborate on if helpful.

15 18jason_sac26, chris_chi24, tampaLisa73 and 12 others
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