🍪 CompoundTalk uses cookies to improve your experience, analyze traffic, and personalize content. By continuing to use this site, you agree to our Cookie Policy.
Evidence-based GLP-1 & peptide discussion since 2023
ForumsClinical Trials & ResearchFLOW trial: semaglutide renal outcomes — anyone have experience? Page 5

FLOW trial: semaglutide renal outcomes — anyone have experience?

steve_okc Sat, Aug 16, 2025 at 3:52 PM 23 replies 1,541 viewsPage 5 of 5
mia_MS2
New Member
8
23
Mar 2026
Ann Arbor, MI
Aug 16, 2025 at 10:57 PM#21

jason_sac26 — that is really helpful context on FLOW trial semaglutide. Follow-up question: what labs did your doctor order to monitor this?

I am in a similar situation (just started) and trying to set realistic expectations.

36 12ricardo_MIA, BrianDallas92, labquiet_amy and 33 others
Reply Quote Save Share Report
MASHdoc_SA
Member
456
2,345
Aug 2024
San Antonio, TX
Aug 16, 2025 at 11:14 PM#22

To answer kim_atl_prep's question specifically:

From a clinical standpoint, FLOW trial semaglutide renal is an area where we have good evidence.

The short answer: baseline labs + quarterly monitoring is the standard of care.

The longer answer involves understanding the mechanism of action at the receptor level, which I am happy to elaborate on if helpful.

48 6TrialTracker_MD, JennaRN, LabKate and 45 others
Reply Quote Save Share Report
tampaLisa73
Member
312
1,456
Oct 2024
Tampa, FL
Aug 16, 2025 at 11:31 PM#23

Thank you mia_MS2! This is incredibly helpful. Bookmarking for later. 🙏

40 15sarah_nash92, FitDadDave, RunnerRach and 37 others
Reply Quote Save Share Report

PeptideMeter — Independent Peptide Analytics

Community-driven peptide testing and vendor rating platform. Transparent results. Unbiased analysis. Trusted by thousands.

View Results
Dr.NateNeph
VIP Member
2,987
16,234
Dec 2023
Houston, TX
Aug 16, 2025 at 11:48 PM#24

Relevant to FLOW trial semaglutide renal — here is my latest bloodwork comparison:

Key improvements: A1C 7.6% → 5.5%, triglycerides 193 → 93 mg/dL, hsCRP 8.0 → 1.1 mg/L. All on tirzepatide for 9 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

44 12B12Beth, RickReta_CO, PharmHunterJen and 41 others
Reply Quote Save Share Report
rick_sfbay
Member
289
1,234
Jan 2025
San Francisco, CA
Aug 17, 2025 at 12:05 AM#25

Slightly tangential to FLOW trial semaglutide but mia_MS2 reminded me — what is the latest on the oral formulations?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

23 13Dr.BariatricHTX, LindaRN_retired, tommy_boulder and 20 others
Reply Quote Save Share Report
1345

Similar Threads

FLOW trial: semaglutide renal outcomes — NEJM publication review14 replies
SELECT trial: semaglutide 2.4mg cardiovascular outcomes — 4yr data9 replies
TRIUMPH program (retatrutide) — Phase 3 trial design and endpoints13 replies
Orforglipron ATTAIN trials — oral non-peptide GLP-1 agonist8 replies
CagriSema (amylin + semaglutide) — REDEFINE Phase 3 results20 replies
ForumsNewTrendingMembersAccount

Log In

Forgot password?
No account? Register