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Evidence-based GLP-1 & peptide discussion since 2023
ForumsCardiovascular OutcomesShould I be worried about my heart rate going up? — anyone have experience?

Should I be worried about my heart rate going up? — anyone have experience?

fiona_VT Sat, Aug 17, 2024 at 3:46 AM 12 replies 1,852 viewsPage 1 of 3
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fiona_VT
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Aug 17, 2024 at 5:11 AM#1

Just had to share this with someone who would understand — should i be worried about my.

Got my latest A1C and I am genuinely emotional right now. 12 months in and the progress is real.

Details in the comments but wanted to start this thread because I think others going through the same thing need to see that it works.

4 22mark_tokyo, hans_munich, jason_sac26 and 1 other
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TirzTom
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Aug 17, 2024 at 5:28 AM#2

Good question. For Should I be worried about my heart, here is what the evidence says:

  • The clinical trial data (SURMOUNT program) supports this approach
  • Real-world results from this community generally confirm the trial findings
  • Individual variation is real — give it at least 8 weeks before judging

Happy to go deeper on any of these points if helpful.

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hans_munich
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Aug 17, 2024 at 5:45 AM#3
TirzTom said:
For Should I be worried about my heart, here is what the evidence says:The clinical trial data (SURM

Completely agree with TirzTom. I would add that Should I be worried about my also has implications for long-term metabolic health that sometimes get overlooked in these discussions.

In my case, following a similar approach led to significant improvements compared to what I was doing before.

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TomFromTexas
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Aug 17, 2024 at 6:02 AM#4

Exactly this. My pharmacist said the same thing about Should I be worried.

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rachel_ABQ
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Albuquerque, NM
Aug 17, 2024 at 6:19 AM#5

As a pharmacist, I want to add some clinical context to this discussion on Should I be worried about my heart rate.

Building on what fiona_VT said — the evidence base here is robust. The key publications to reference are from the SELECT program[1].

Key clinical points:

  1. Efficacy is dose-dependent and typically requires 4-5 weeks to reach steady state
  2. Side effect profile is predictable and usually manageable with standard protocols
  3. Monitoring should include baseline labs and follow-up at 3-month intervals
  4. Patient education significantly improves outcomes and adherence

Standard disclaimer: this is educational, not individualized medical advice.

References:
[1] See thread title for relevant study identification.
29 24Dr.CardioMD, EndoResFellow, PharmacoVig_BOS and 26 others
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