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Evidence-based GLP-1 & peptide discussion since 2023
ForumsLab Results & BiomarkersUric acid trends on GLP-1 — anyone have experience? Page 2

Uric acid trends on GLP-1 — anyone have experience?

claudia_zurich Sun, Nov 23, 2025 at 3:02 PM 17 replies 1,125 viewsPage 2 of 4
DebRD_ATL
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Nov 23, 2025 at 5:52 PM#6

Subscribing to this thread. Uric acid trends on GLP-1 is exactly what I've been researching. 🙏

43 18BiostatsBrad, PeptideSynthNJ, Dr.KarenChen and 40 others
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Dr.CardioMD
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Nov 23, 2025 at 6:09 PM#7

As a pharmacist, I want to add some clinical context to this discussion on Uric acid trends on GLP-1 anyone have.

Building on what Dr.PulmRoch said — the evidence base here is robust. The key publications to reference are from the SURMOUNT program[1].

Key clinical points:

  1. Efficacy is dose-dependent and typically requires 4-5 weeks to reach steady state
  2. Side effect profile is predictable and usually manageable with standard protocols
  3. Monitoring should include baseline labs and follow-up at 3-month intervals
  4. Patient education significantly improves outcomes and adherence

Standard disclaimer: this is educational, not individualized medical advice.

References:
[1] See thread title for relevant study identification.
Last edited: Nov 24, 2025 at 12:09 AM
20 15Dr.NephBHM_UK, kim_atl_prep, sarah_TO and 17 others
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SallyK_inj
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Nov 23, 2025 at 6:26 PM#8

Reading this thread on Uric acid trends on GLP-1 hits close to home. Dad of 2 checking in — I started at 277 lbs and felt like I would tried everything.

13 months on tirz and I am a different person. Not just the 52 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about Uric acid trends on — take the leap. It was the best health decision I have ever made. ❤️

19 8oliver_london, tane_welly, Dr.PathRoch and 16 others
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NurseLeah_Nash
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Nov 23, 2025 at 6:43 PM#9

Dr.LipidDallas — that is really helpful context on Uric acid trends on GLP-1. Follow-up question: how long did you wait before increasing your dose?

I am in a similar situation (week 4) and trying to set realistic expectations.

Last edited: Nov 23, 2025 at 7:43 PM
49 3Dr.KarenChen, Dr.NateNeph, PharmD_Rodriguez and 46 others
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anders_CPH
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Nov 23, 2025 at 7:00 PM#10

To answer SallyK_inj's question specifically:

From a clinical standpoint, Uric acid trends on GLP-1 is a reasonable concern that deserves a thorough answer.

The short answer: the evidence supports this approach for most patients.

The longer answer involves reviewing the specific clinical trial data relevant to your question, which I am happy to elaborate on if helpful.

Last edited: Nov 23, 2025 at 11:00 PM
42 14ChrisMacros, KetoKyle, CanadaChris and 39 others
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