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Evidence-based GLP-1 & peptide discussion since 2023
ForumsLab Results & BiomarkersMy 12-month lab diary — looking for input

My 12-month lab diary — looking for input

pete_RVA Wed, Nov 12, 2025 at 9:47 PM 12 replies 961 viewsPage 1 of 3
pete_RVA
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Dec 2024
Richmond, VA
Nov 12, 2025 at 11:12 PM#1

Hot take incoming: my 12-month lab diary looking for.

I know this is controversial here but I think the conventional wisdom on this topic might be overly simplistic. Before you grab your pitchforks, hear me out.

My argument is based on conversations with my provider who has a different perspective.

Change my mind. Seriously — I want to be wrong about this if I am.

43 8mike_mod, SarahChen_PharmD, sarah.morrison and 40 others
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NeuroNate
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Dec 2023
Chicago, IL
Nov 12, 2025 at 11:29 PM#2

pete_RVA's experience with My 12-month lab diary resonates deeply with mine. I went through almost the identical process — starting dose, titration timeline, side effects, everything.

The main difference: I titrated faster. But the overall trajectory has been remarkably similar. Down 52 lbs in 7 months.

One thing I would add that pete_RVA did not mention: the relationship with food fundamentally changed.

15 22wendy_avl, jason_paloalto, Dr.LeslieOBGYN and 12 others
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ingrid_STO
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Stockholm, SE
Nov 12, 2025 at 11:46 PM#3

Thanks for sharing this, pete_RVA. A few questions about your My 12-month lab experience:

  1. What dose are you currently on?
  2. How long before you noticed significant changes?
  3. Did your doctor have any specific recommendations about My 12-month lab?

I am in a similar boat and trying to learn from others' experiences before my next appointment.

22 13MikeFit_NJ, InsuranceTom, WendyG_ATL and 19 others
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pete_RVA
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Dec 2024
Richmond, VA
Nov 13, 2025 at 12:03 AM#4

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on My 12-month lab diary .

To answer ingrid_STO: yes, I am on compounded sema from a 503B pharmacy.

Quick update: things are still going well. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

44 21MikeNYC_runner and 41 others
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LabKate
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Oregon
Nov 13, 2025 at 12:20 AM#5

Relevant to My 12-month lab diary looking — here is my latest bloodwork comparison:

Key improvements: A1C 7.6% → 5.5%, triglycerides 225 → 95 mg/dL, hsCRP 8.0 → 1.3 mg/L. All on tirzepatide for 17 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

Last edited: Nov 13, 2025 at 3:20 AM
38 3labquiet_amy, emily_PDX, Dr.SleepRoch and 35 others
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