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Evidence-based GLP-1 & peptide discussion since 2023
ForumsLab Results & BiomarkersCortisol and GLP-1 — need advice Page 9

Cortisol and GLP-1 — need advice

NurseLeah_Nash Fri, Nov 7, 2025 at 8:41 AM 43 replies 1,438 viewsPage 9 of 9
sarah_TO
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Sep 2024
Toronto, CA
Nov 7, 2025 at 9:26 PM#41

Want to share my personal experience related to Cortisol and GLP-1 need since I think it might help others in a similar situation.

I started my GLP-1 journey in October 2024 at 276 lbs with prediabetes and hypertension. My endocrinologist prescribed semaglutide 0.25mg to start.

Now, 18 months later: I am down 71 lbs, my labs have normalized, and I am off 2 of my 3 medications. The Cortisol and GLP-1 aspect specifically was something that made a big difference in my journey.

This community helped me every step of the way.

13 5andrew_nyc, Dr.EndoEP, GraceAZ_72 and 10 others
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TomTeleRx
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189
678
Feb 2025
Delaware
Nov 7, 2025 at 9:43 PM#42

wendy_avl — that is really helpful context on Cortisol and GLP-1 need. Follow-up question: did you experience any side effects during this phase?

I am in a similar situation (about to start) and trying to set realistic expectations.

Last edited: Nov 7, 2025 at 10:43 PM
3 19bri_stats, pete_manc_UK, anna.melb_AU
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MASHdoc_SA
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456
2,345
Aug 2024
San Antonio, TX
Nov 7, 2025 at 10:00 PM#43

Want to share my personal experience related to Cortisol and GLP-1 need since I think it might help others in a similar situation.

I started my GLP-1 journey in March 2025 at 248 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.

Now, 10 months later: I am down 78 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The Cortisol and GLP-1 aspect specifically was something that made a big difference in my journey.

This forum was my go-to resource throughout.

Last edited: Nov 8, 2025 at 1:00 AM
21 20JennaRN, LabKate, kate.chem and 18 others
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Dr.ObesityLA
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Dec 2023
Los Angeles, CA
Nov 7, 2025 at 10:17 PM#44

Just wanted to say — for anyone reading this Cortisol and GLP-1 thread who is feeling discouraged: it gets better. The first few weeks are the hardest. Hang in there. 💪

Last edited: Nov 7, 2025 at 11:17 PM
2 21chris_chi24, tampaLisa73
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emma_london
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Oct 2024
London, UK
Nov 7, 2025 at 10:34 PM#45

Subscribing to this thread. Cortisol and GLP-1 need is exactly what I've been researching. 🙏

19 4julia.endo, JessicaM_2024, TomFromTexas and 16 others
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