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ForumsRetatrutide & Triple AgonistsReta hype is insane but I am cautiously optimistic Page 3

Reta hype is insane but I am cautiously optimistic

SkepticalSean Fri, Jan 16, 2026 at 2:57 AM 11 replies 731 viewsPage 3 of 3
newstart_MO
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Jan 16, 2026 at 7:12 AM#11
TirzTom said:
Reta hype is insane but I am is not that straightforward in my experience

This is exactly right. TirzTom articulated what I have been trying to explain to my doctor for months. The Reta hype is insane but I aspect is the most important factor.

Last edited: Jan 16, 2026 at 1:12 PM
8 3bri_stats, pete_manc_UK, anna.melb_AU and 5 others
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LondonLisa
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Jan 16, 2026 at 7:29 AM#12

Reading this thread on Reta hype is insane but I hits close to home. Night shift nurse — I started at 299 lbs and felt like I would tried everything.

15 months on tirz and I am a different person. Not just the 74 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about Reta hype is insane — take the leap. It was the best health decision I have ever made. ❤️

19 7Dr.MetabolicMD, RetaRick_CA, JenPlateau and 16 others
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hans_munich
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Munich, DE
Jan 16, 2026 at 7:46 AM#13

VendorMark — that is really helpful context on Reta hype is insane but I. Follow-up question: what labs did your doctor order to monitor this?

I am in a similar situation (just started) and trying to set realistic expectations.

49 11Dr.LipidDallas, alex_tucson, kevin_tulsa and 46 others
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LibrarianMeg
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Jan 16, 2026 at 8:03 AM#14

To answer LondonLisa's question specifically:

From a clinical standpoint, Reta hype is insane but I am is an area where we have good evidence.

The short answer: baseline labs + quarterly monitoring is the standard of care.

The longer answer involves understanding the mechanism of action at the receptor level, which I am happy to elaborate on if helpful.

6 24JessicaM_2024, TomFromTexas, mike.trainer_LA and 3 others
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ricardo_MIA
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Jan 16, 2026 at 8:20 AM#15

Bookmarked 📌 The Reta hype is insane info in this thread is essential. Coming back to this for sure.

19 13ChrisMacros, KetoKyle, CanadaChris and 16 others
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