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Evidence-based GLP-1 & peptide discussion since 2023
ForumsRetatrutide & Triple Agonists24% weight loss number blew my mind - please be real Page 2

24% weight loss number blew my mind - please be real

JenPlateau Mon, Jan 12, 2026 at 7:40 AM 23 replies 930 viewsPage 2 of 5
matt_MKE
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1,345
Sep 2024
Milwaukee, WI
Jan 12, 2026 at 10:30 AM#6

Subscribing to this thread. 24% weight loss number is exactly what I've been researching. 🙏

Last edited: Jan 12, 2026 at 1:30 PM
23 20andrew_nyc, Dr.EndoEP, GraceAZ_72 and 20 others
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JenPlateau
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Nov 2024
Missouri
Jan 12, 2026 at 10:47 AM#7

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on 24% weight loss number.

To answer TrialNerd_Beth: my doctor and I discussed the options and went with brand.

Quick update: I have noticed more improvement since posting this. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

Last edited: Jan 12, 2026 at 4:47 PM
45 10TrialNerd_Beth, HPLC_Greg, LibrarianMeg and 42 others
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lucas_SP_BR
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Jun 2024
São Paulo, BR
Jan 12, 2026 at 11:04 AM#8

Adding my data to this 24% weight loss number discussion:

MetricBaselineMonth 4Month 6
Weight260 lbs230 lbs205 lbs
A1C6.4%6.2%5.2%
hsCRP4.03.01.0

Protocol: Tirzepatide 15mg/wk, resistance training 3x/wk, protein 1.2g/kg/day.

13 9zoe_NC, Dr.ObesityLA, NurseKim_ATL and 10 others
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DataDave
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Apr 2024
Washington
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Jan 12, 2026 at 11:21 AM#9

+1 to JenPlateau. Especially the point about "Thank you all for the thoughtful replies..." — I have seen the same in my own experience with 24% weight loss number.

40 18amsterdam_pete, LondonLisa, mike_nyc and 37 others
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jim_asheville
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1,234
Aug 2024
Asheville, NC
Jan 12, 2026 at 11:38 AM#10

Slightly tangential to 24% weight loss number but LondonLisa reminded me — what is the latest on the oral formulations?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

Last edited: Jan 12, 2026 at 2:38 PM
9 13LarryQC_SD, wanda_boise, NurseAsh_DET and 6 others
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