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ForumsRetatrutide & Triple AgonistsRetatrutide mechanism: GLP-1/GIP/glucagon triple agonism explained — anyone have experience? Page 4

Retatrutide mechanism: GLP-1/GIP/glucagon triple agonism explained — anyone have experience?

mel_PDX Wed, Dec 31, 2025 at 3:52 AM 23 replies 773 viewsPage 4 of 5
DadBodDave
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Nov 2024
Ohio
Dec 31, 2025 at 9:32 AM#16

Congrats LibrarianMeg!! Keep going — you're doing incredible. 🎉 👏

47 21laura_annarbor, JenMemphis, pat_auckland and 44 others
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bri_stats
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May 2024
Seattle, WA
Dec 31, 2025 at 9:49 AM#17

Reading this thread on Retatrutide mechanism hits close to home. Night shift nurse — I started at 287 lbs and felt like I would tried everything.

13 months on tirz and I am a different person. Not just the 62 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about Retatrutide — take the leap. It was the best health decision I have ever made. ❤️

Last edited: Dec 31, 2025 at 1:49 PM
31 18mike.trainer_LA, sarah_nash92, FitDadDave and 28 others
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ricardo_MIA
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Miami, FL
Dec 31, 2025 at 10:06 AM#18

mike_nyc — that is really helpful context on Retatrutide mechanism. Follow-up question: what labs did your doctor order to monitor this?

I am in a similar situation (just started) and trying to set realistic expectations.

Last edited: Dec 31, 2025 at 3:06 PM
28 14CanadaChris, ZaraB_AL, JakeSmashed95 and 25 others
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traveltech_sara
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Jan 2025
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Dec 31, 2025 at 10:23 AM#19

Reading this thread on Retatrutide mechanism hits close to home. Dad of 2 checking in — I started at 269 lbs and felt like I would tried everything.

15 months on tirz and I am a different person. Not just the 44 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about Retatrutide — take the leap. It was the best health decision I have ever made. ❤️

Last edited: Dec 31, 2025 at 1:23 PM
38 17NurseAsh_DET, BenResearch_OR, MikeKY_noInsulin and 35 others
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CanadaChris
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Toronto, CA
Dec 31, 2025 at 10:40 AM#20

traveltech_sara — that is really helpful context on Retatrutide mechanism. Follow-up question: how long did you wait before increasing your dose?

I am in a similar situation (week 4) and trying to set realistic expectations.

Last edited: Dec 31, 2025 at 4:40 PM
29 3lori_vegas, Dr.PulmRoch, maya_sedona and 26 others
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