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ForumsTirzepatide (Mounjaro / Zepbound)Has anyone dealt with tirzepatide dual agonism: gip + glp-1 synergistic mechanism? Page 7

Has anyone dealt with tirzepatide dual agonism: gip + glp-1 synergistic mechanism?

robert_kc Tue, Jan 9, 2024 at 12:28 AM 49 replies 2,765 viewsPage 7 of 10
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Jan 9, 2024 at 10:23 AM#31

Bookmarked 📌 The Has anyone dealt info in this thread is essential. Coming back to this for sure.

16 12PedsEndoPhilly, SleepDoc_PDX, RegAffairsDC and 13 others
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adam_van
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Jan 9, 2024 at 10:40 AM#32

LibrarianMeg — that is really helpful context on Has anyone dealt with. Follow-up question: did you change anything about your diet at the same time?

I am in a similar situation (month 2) and trying to set realistic expectations.

15 6Dr.BariatricHTX, LindaRN_retired, tommy_boulder and 12 others
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robert_kc
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Jan 9, 2024 at 10:57 AM#33

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Has anyone dealt with.

To answer robert_kc: yes, I am on compounded sema from a 503B pharmacy.

Quick update: things are still going well. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

7 23DoseLogDan, SleepFixSam, PurityPaulOR and 4 others
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nancy_portland
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Jan 9, 2024 at 11:14 AM#34

LibrarianMeg — that is really helpful context on Has anyone dealt with. Follow-up question: did you experience any side effects during this phase?

I am in a similar situation (about to start) and trying to set realistic expectations.

30 9Dr.PeteFamMed, claudia_zurich, nancy_portland and 27 others
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kevin_tulsa
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Jan 9, 2024 at 11:31 AM#35

Want to share my personal experience related to Has anyone dealt with since I think it might help others in a similar situation.

I started my GLP-1 journey in March 2025 at 274 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.

Now, 12 months later: I am down 39 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The Has anyone dealt aspect specifically was something that made a big difference in my journey.

This forum was my go-to resource throughout.

17 14NurseLeah_Nash, gary_naperville, sean_dublin and 14 others
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