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Evidence-based GLP-1 & peptide discussion since 2023
ForumsVerified VendorsMy honest comparison after ordering from all 3 Page 4

My honest comparison after ordering from all 3

MikeFit_NJ Mon, Feb 23, 2026 at 4:53 AM 34 replies 589 viewsPage 4 of 7
MikeFit_NJ
Senior Member
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Apr 2024
New Jersey
Feb 23, 2026 at 10:33 AM#16

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on My honest comparison.

To answer roxy_nash: yes, I am on compounded sema from a 503B pharmacy.

Quick update: things are still going well. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

30 18LeilaHI, marcus_mpls, DeniseRN_TPA and 27 others
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josh_phd_bmore
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Jul 2024
Baltimore, MD
Feb 23, 2026 at 10:50 AM#17

Relevant to My honest comparison after — here is my latest bloodwork comparison:

Key improvements: A1C 7.6% → 5.5%, triglycerides 241 → 111 mg/dL, hsCRP 8.0 → 1.1 mg/L. All on tirzepatide for 9 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

Last edited: Feb 23, 2026 at 12:50 PM
14 16Dr.ObesityLA, NurseKim_ATL, paul_denver and 11 others
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mona_PHX
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Dec 2024
Phoenix, AZ
Feb 23, 2026 at 11:07 AM#18

100%. My provider said the same thing about My honest comparison.

35 0SallyK_inj, CryptoCarl, MariaRD and 32 others
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Dr.NutriCornell
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Mar 2024
Ithaca, NY
Feb 23, 2026 at 11:24 AM#19

Slightly tangential to My honest comparison but tane_welly reminded me — does anyone have experience combining this with metformin?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

37 13JenMemphis, pat_auckland, Dr.GastroMayo and 34 others
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RetaRick_CA
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Jan 2024
California
Feb 23, 2026 at 11:41 AM#20
MikeFit_NJ said:
Thank you all for the thoughtful replies on My honest comparison

This is exactly right. MikeFit_NJ articulated what I have been trying to explain to my doctor for months. The My honest comparison aspect is the most important factor.

39 1MounjBrad, nick_newbie, DadBodDave and 36 others
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