Apr 16, 2025 at 6:06 PM#36
Bookmarked 📌 The Orforglipron info in this thread is essential. Coming back to this for sure.
50 24anna.melb_AU, mark_tokyo, hans_munich and 47 others
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Apr 16, 2025 at 6:23 PM#37
Slightly tangential to Orforglipron ATTAIN-4 my but Dr.EndoEP reminded me — does anyone have experience combining this with metformin?
I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.
19 19Dr.SurgeonPGH, rachel_ABQ, traveltech_sara and 16 others
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Apr 16, 2025 at 6:40 PM#38
Adding my data to this Orforglipron ATTAIN-4 my discussion:
| Metric | Baseline | Month 4 | Month 6 |
|---|---|---|---|
| Weight | 244 lbs | 234 lbs | 199 lbs |
| A1C | 6.8% | 6.2% | 5.2% |
| hsCRP | 8.0 | 3.0 | 1.0 |
Protocol: Tirzepatide 15mg/wk, resistance training 3x/wk, protein 1.6g/kg/day.
27 9maya_sedona, stefan_berlin, Dr.EM_Chicago and 24 others
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View ResultsApr 16, 2025 at 6:57 PM#39
Reading this thread on Orforglipron ATTAIN-4 my hits close to home. Night shift nurse — I started at 295 lbs and felt like I would tried everything.
11 months on tirz and I am a different person. Not just the 70 lbs lost — my energy, my mood, my relationship with food. All transformed.
If you are on the fence about Orforglipron — take the leap. It was the best health decision I have ever made. ❤️
Last edited: Apr 16, 2025 at 9:57 PM
46 8FDA_TrackerJim, ricardo_MIA, BrianDallas92 and 43 others
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Apr 16, 2025 at 7:14 PM#40
paige_pharma — that is really helpful context on Orforglipron ATTAIN-4 my. Follow-up question: what labs did your doctor order to monitor this?
I am in a similar situation (just started) and trying to set realistic expectations.
7 11NurseLeah_Nash, gary_naperville, sean_dublin and 4 others
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