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Evidence-based GLP-1 & peptide discussion since 2023
ForumsCardiovascular OutcomesHas anyone dealt with coronary artery calcium score changes on glp-1? Page 3

Has anyone dealt with coronary artery calcium score changes on glp-1?

KarenAZ_mom Mon, Jan 8, 2024 at 11:16 PM 35 replies 2,233 viewsPage 3 of 7
mel_PDX
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Jan 9, 2024 at 3:31 AM#11

Dr.AddMedPHL — wow. This community is amazing.

27 7Dr.NateNeph, PharmD_Rodriguez, julia.endo and 24 others
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claudia_zurich
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Jan 9, 2024 at 3:48 AM#12

Slightly tangential to Has anyone dealt with but KarenAZ_mom reminded me — what is the latest on the oral formulations?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

35 0tammy_FL, Dr.LipidDallas, alex_tucson and 32 others
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tom_AK
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Jan 9, 2024 at 4:05 AM#13

Thanks for sharing this, KarenAZ_mom. A few questions about your Has anyone dealt experience:

  1. What dose did you start at?
  2. How long before you noticed side effects improving?
  3. Did your provider have any specific recommendations about Has anyone deal?

I am in a similar boat and trying to learn from others' experiences before my next appointment.

25 13tyler_CSCS, VanRx_Mike, steve_okc and 22 others
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KarenAZ_mom
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Scottsdale, AZ
Jan 9, 2024 at 4:22 AM#14

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Has anyone dealt with.

To answer claudia_zurich: yes, I am on compounded sema from a 503B pharmacy.

Quick update: things are still going well. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

Last edited: Jan 9, 2024 at 9:22 AM
8 13LibrarianMeg, bri_stats, pete_manc_UK and 5 others
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Dr.RaviCardio
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Jan 9, 2024 at 4:39 AM#15

Relevant to Has anyone dealt with coronary — here is my latest bloodwork comparison:

Key improvements: A1C 8.4% → 5.5%, triglycerides 205 → 105 mg/dL, hsCRP 8.0 → 1.1 mg/L. All on tirzepatide for 9 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

27 1jason_sac26, chris_chi24, tampaLisa73 and 24 others
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