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Evidence-based GLP-1 & peptide discussion since 2023
ForumsLab Results & BiomarkersHormone panel changes — anyone have experience? Page 2

Hormone panel changes — anyone have experience?

PharmHunterJen Fri, Aug 15, 2025 at 10:40 PM 16 replies 1,238 viewsPage 2 of 4
julia.endo
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Aug 16, 2025 at 1:30 AM#6

The sleep piece resonates hard with me. I'm a nurse doing 12-hour night shifts and my weight loss has been slower than most people I see posting here. I average about 5 hours of broken sleep on work days. I wonder how much that's holding me back.

20 23anna.melb_AU, mark_tokyo, hans_munich and 17 others
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LindaRN_retired
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Dec 2024
Sarasota, FL
Aug 16, 2025 at 1:47 AM#7

Sleep deprivation is enormously underappreciated as a factor in weight management. There are studies showing that people in a caloric deficit who sleep 5.5 hours lose 55% less fat and 60% more lean mass compared to those sleeping 8.5 hours — same caloric intake. Shift workers consistently show higher rates of obesity, metabolic syndrome, and cardiovascular disease, and disrupted circadian rhythm is a major contributor.

I know you can't always control your schedule, but even small improvements — blackout curtains, consistent wake times on days off, limiting caffeine 8+ hours before sleep — can help.

23 17Dr.GutHealth, amsterdam_pete, LondonLisa and 20 others
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jason_paloalto
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Palo Alto, CA
Aug 16, 2025 at 2:04 AM#8

Looking at the OP's numbers from a trends perspective: the "plateau" from week 14-19 actually shows a slight downward trend if you plot it. 222 → 219 over 5 weeks is about 0.6 lbs/week. That's not zero — it's just much slower than the 2.3-3.0 lbs/week she was losing before.

Psychologically, going from 3 lbs/week to 0.6 lbs/week feels like a plateau even though progress is technically still happening. This is why I always recommend plotting a 7-day moving average rather than looking at individual weigh-ins. Daily weight fluctuations of 2-4 lbs are completely normal due to water, sodium, and digestive contents.

49 7mona_PHX, andrew_nyc, Dr.EndoEP and 46 others
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