+1. This mirrors my journey exactly. The Arterial stiffness discussion here is so valuable.

mike.trainer_LA said:

Night shift nurse — I started at 267 lbs and felt like I would tried everything

I respect mike.trainer_LA perspective but I think this oversimplifies things a bit. Re: Arterial stiffness reduction — the effect size varies considerably by population.

I am not saying mike.trainer_LA wrong entirely — just that the picture is more nuanced than a blanket statement. The SURMOUNT data specifically shows baseline BMI-dependent responses.

Reading this thread on Arterial stiffness hits close to home. Dad of 2 checking in — I started at 293 lbs and felt like I would tried everything.

9 months on tirz and I am a different person. Not just the 68 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about Arterial stiffness — take the leap. It was the best health decision I have ever made. ❤️

Bookmarked 📌 The Arterial stiffness info in this thread is essential. Coming back to this for sure.

mel_PDX — that is really helpful context on Arterial stiffness. Follow-up question: did you experience any side effects during this phase?

I am in a similar situation (about to start) and trying to set realistic expectations.