Jul 24, 2025 at 9:15 PM#11
Thank you COA_Karl! This is incredibly helpful. Taking this to my next appointment. 🙏
Last edited: Jul 25, 2025 at 3:15 AM
23 3pam_stl, wei_SG, cory_ATX and 20 others
Reply Quote Save Share Report
Jul 24, 2025 at 9:32 PM#12
Slightly tangential to Testosterone changes on but GenomicsKate reminded me — does anyone have experience combining this with metformin?
I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.
21 6Dr.PathRoch, mona_PHX, andrew_nyc and 18 others
Reply Quote Save Share Report
Jul 24, 2025 at 9:49 PM#13
Thanks for sharing this, GenomicsKate. A few questions about your Testosterone changes experience:
- What dose did you start at?
- How long before you noticed side effects improving?
- Did your provider have any specific recommendations about Testosterone?
I am in a similar boat and trying to learn from others' experiences before my next appointment.
39 23alex_tucson, kevin_tulsa, Dr.PainCLE and 36 others
Reply Quote Save Share Report
Sigma-Aldrich — Research-Grade Standards
Certified reference materials, analytical reagents, and research-grade standards for peptide verification. Trusted by laboratories worldwide.
Shop Reference StandardsJul 24, 2025 at 10:06 PM#14
OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Testosterone changes on.
To answer quinn_sf: I started tracking everything in a spreadsheet from day 1.
Quick update: I will post a proper update thread soon. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏
Last edited: Jul 25, 2025 at 3:06 AM
13 6Dr.PeteFamMed, claudia_zurich, nancy_portland and 10 others
Reply Quote Save Share Report
Jul 24, 2025 at 10:23 PM#15
Adding my data to this Testosterone changes on discussion:
| Metric | Baseline | Month 3 | Month 8 |
|---|---|---|---|
| Weight | 242 lbs | 247 lbs | 207 lbs |
| A1C | 6.6% | 5.8% | 5.4% |
| hsCRP | 6.0 | 2.0 | 0.8 |
Protocol: Semaglutide 2.4mg/wk, resistance training 3x/wk, protein 1.4g/kg/day.
Last edited: Jul 25, 2025 at 4:23 AM
13 3Dr.MetabolicMD, RetaRick_CA, JenPlateau and 10 others
Reply Quote Save Share Report