🍪 CompoundTalk uses cookies to improve your experience, analyze traffic, and personalize content. By continuing to use this site, you agree to our Cookie Policy.
Evidence-based GLP-1 & peptide discussion since 2023
ForumsRetatrutide & Triple AgonistsRetatrutide dose-escalation protocol — 6 month update Page 3

Retatrutide dose-escalation protocol — 6 month update

HealthEcon_DC Sun, Nov 2, 2025 at 7:56 AM 11 replies 909 viewsPage 3 of 3
fiona_VT
Member
178
890
Dec 2024
Vermont
Nov 2, 2025 at 12:11 PM#11

HPLC_Greg — wow. I've been looking for this exact info for weeks.

14 14mark_tokyo, hans_munich, jason_sac26 and 11 others
Reply Quote Save Share Report
Admin
Administrator
2,456
9,812
Oct 2023
Online
Nov 2, 2025 at 12:28 PM#12

Slightly tangential to Retatrutide but HealthEcon_DC reminded me — has anyone else noticed changes in their alcohol tolerance?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

20 12SleepDoc_PDX, RegAffairsDC, BiostatsBrad and 17 others
Reply Quote Save Share Report
RegAffairsDC
Member
678
3,456
May 2024
Washington, DC
Nov 2, 2025 at 12:45 PM#13

Thanks for sharing this, HealthEcon_DC. A few questions about your Retatrutide experience:

  1. What dose worked best for you?
  2. How long before you noticed appetite suppression kicking in?
  3. Did your endo have any specific recommendations about Retatrutide?

I am in a similar boat and trying to learn from others' experiences before my next appointment.

45 12hannah_MT, Dr.SportsMedIN, amy_econ_NJ and 42 others
Reply Quote Save Share Report

Sigma-Aldrich — Research-Grade Standards

Certified reference materials, analytical reagents, and research-grade standards for peptide verification. Trusted by laboratories worldwide.

Shop Reference Standards
HealthEcon_DC
Member
567
3,456
Apr 2024
Washington, DC
Nov 2, 2025 at 1:02 PM#14

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Retatrutide.

To answer Admin: I get my labs done through Quest every 3 months.

Quick update: my latest labs came back even better. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

Last edited: Nov 2, 2025 at 3:02 PM
30 18TirzTom, TrialTracker_MD, JennaRN and 27 others
Reply Quote Save Share Report
dave_SLC
Member
345
1,567
Aug 2024
Salt Lake City, UT
Nov 2, 2025 at 1:19 PM#15

Relevant to Retatrutide dose-escalation — here is my latest bloodwork comparison:

Key improvements: A1C 7.2% → 5.3%, triglycerides 203 → 103 mg/dL, hsCRP 6.0 → 0.9 mg/L. All on tirzepatide for 7 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

8 24Dr.BariatricHTX, LindaRN_retired, tommy_boulder and 5 others
Reply Quote Save Share Report

Similar Threads

TRIUMPH-3 topline results — 24.2% body weight loss at 48 weeks10 replies
Retatrutide mechanism: GLP-1/GIP/glucagon triple agonism explained5 replies
Retatrutide Phase 2 dose-response analysis — optimal dose range10 replies
Glucagon receptor agonism and hepatic lipid oxidation — MASH implications13 replies
Retatrutide vs tirzepatide — dual vs triple agonist comparison22 replies
ForumsNewTrendingMembersAccount

Log In

Forgot password?
No account? Register