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Evidence-based GLP-1 & peptide discussion since 2023
ForumsCardiovascular OutcomesNNT for MACE prevention — what worked for you? Page 2

NNT for MACE prevention — what worked for you?

Dr.LipidDallas Sun, Oct 29, 2023 at 1:42 AM 16 replies 2,206 viewsPage 2 of 4
Dr.MetabolicMD
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Oct 29, 2023 at 4:32 AM#6
JennaRN said:
For NNT for MACE prevention what, here is what the evidence says:The clinical trial data (SURMOUNT

Gonna push back on this one. NNT for MACE prevention what is not that straightforward in my experience. I have been on this for 12 months and the reality is messier than the trials suggest.

Don't get me wrong — the medication works. But cost accessibility is a real barrier. We should be honest about that.

Last edited: Oct 29, 2023 at 6:32 AM
32 3SleepDoc_PDX, RegAffairsDC, BiostatsBrad and 29 others
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stefan_berlin
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Oct 29, 2023 at 4:49 AM#7

Adding my data to this NNT for MACE prevention discussion:

MetricBaselineMonth 4Month 6
Weight268 lbs238 lbs223 lbs
A1C7.2%6.2%5.2%
hsCRP7.03.01.0

Protocol: Tirzepatide 15mg/wk, resistance training 3x/wk, protein 1.5g/kg/day.

29 15JessicaH_TX, KevinCompounds, TirzTom and 26 others
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MikeNYC_runner
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Oct 29, 2023 at 5:06 AM#8

roxy_nash — wow. This community is amazing.

12 22Dr.ObesityMed, HealthEcon_DC, PedsEndoPhilly and 9 others
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jason_sac26
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Oct 29, 2023 at 5:23 AM#9

Slightly tangential to NNT for MACE prevention but NauseaFreeNow reminded me — what is the latest on the oral formulations?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

24 18maya_sedona, stefan_berlin, Dr.EM_Chicago and 21 others
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mike_mod
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Oct 29, 2023 at 5:40 AM#10

Moderator note: Please keep vendor-specific discussions in the Vendor Reviews section.

I have cleaned up a few off-topic posts. 👍

Last edited: Oct 29, 2023 at 7:40 AM
49 4PurityPaulOR, MaxMetOK, MounjBrad and 46 others
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