🍪 CompoundTalk uses cookies to improve your experience, analyze traffic, and personalize content. By continuing to use this site, you agree to our Cookie Policy.
Evidence-based GLP-1 & peptide discussion since 2023
ForumsCardiovascular OutcomesNNT for MACE prevention — what worked for you? Page 3

NNT for MACE prevention — what worked for you?

Dr.LipidDallas Sun, Oct 29, 2023 at 1:42 AM 16 replies 2,206 viewsPage 3 of 4
Dr.PeteFamMed
Senior Member
2,012
9,234
Jan 2024
Minneapolis, MN
Oct 29, 2023 at 5:57 AM#11
Dr.MetabolicMD said:
NNT for MACE prevention what is not that straightforward in my experience

This is exactly right. Dr.MetabolicMD articulated what I have been trying to explain to my doctor for months. The NNT for MACE prevention aspect is the most important factor.

1 14hyun_seoul
Reply Quote Save Share Report
andrew_nyc
Member
534
2,345
Apr 2024
New York, NY
Oct 29, 2023 at 6:14 AM#12

Reading this thread on NNT for MACE prevention hits close to home. Night shift nurse — I started at 283 lbs and felt like I would tried everything.

9 months on tirz and I am a different person. Not just the 58 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about NNT for MACE — take the leap. It was the best health decision I have ever made. ❤️

Last edited: Oct 29, 2023 at 11:14 AM
40 24Dr.NateNeph, PharmD_Rodriguez, julia.endo and 37 others
Reply Quote Save Share Report
KetoKyle
Member
678
3,456
Jul 2024
Utah
Oct 29, 2023 at 6:31 AM#13

roxy_nash — that is really helpful context on NNT for MACE prevention . Follow-up question: what labs did your doctor order to monitor this?

I am in a similar situation (just started) and trying to set realistic expectations.

28 7pat_auckland, Dr.GastroMayo, JakeBK_lifts and 25 others
Reply Quote Save Share Report

Janoshik Analytical — Independent Testing

Trusted third-party HPLC & mass spectrometry analysis. Verify peptide purity with the lab the community relies on. Independent. Accurate. Transparent.

Verify Your Peptides
VendorMark
Senior Member
3,456
14,567
Jan 2024
Texas
Online
Oct 29, 2023 at 6:48 AM#14

To answer andrew_nyc's question specifically:

From a clinical standpoint, NNT for MACE prevention what is an area where we have good evidence.

The short answer: baseline labs + quarterly monitoring is the standard of care.

The longer answer involves understanding the mechanism of action at the receptor level, which I am happy to elaborate on if helpful.

23 17Dr.PeteFamMed, claudia_zurich, nancy_portland and 20 others
Reply Quote Save Share Report
LipidDoc_ATL
Senior Member
1,123
5,678
Apr 2024
Atlanta, GA
Oct 29, 2023 at 7:05 AM#15

Bookmarked 📌 The NNT for MACE info in this thread is essential. Coming back to this for sure.

10 5KristenIndy, MarkLI_maint, Dr.PeteFamMed and 7 others
Reply Quote Save Share Report

Similar Threads

SELECT trial: 20% MACE reduction — mechanistic deep dive7 replies
Semaglutide cardiovascular benefit independent of weight loss11 replies
STEP-HFpEF: semaglutide in heart failure with preserved EF15 replies
GLP-1 and arterial inflammation — hsCRP and IL-6 reduction data18 replies
Lp(a) on GLP-1 agonists — any impact on this risk factor?8 replies
ForumsNewTrendingMembersAccount

Log In

Forgot password?
No account? Register