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Evidence-based GLP-1 & peptide discussion since 2023
ForumsLab Results & BiomarkersGGT as a liver health marker — anyone have experience? Page 5

GGT as a liver health marker — anyone have experience?

robert_kc Sun, Jun 15, 2025 at 3:49 AM 24 replies 1,412 viewsPage 5 of 5
hannah_MT
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Bozeman, MT
Jun 15, 2025 at 10:54 AM#21

steph_laguna — that is really helpful context on GGT as a liver health. Follow-up question: what labs did your doctor order to monitor this?

I am in a similar situation (just started) and trying to set realistic expectations.

Last edited: Jun 15, 2025 at 1:54 PM
42 12nick_newbie, DadBodDave, AmyNC_wife and 39 others
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Dr.SleepRoch
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Apr 2024
Rochester, MN
Jun 15, 2025 at 11:11 AM#22

To answer JessicaM_2024's question specifically:

From a clinical standpoint, GGT as a liver health marker is an area where we have good evidence.

The short answer: baseline labs + quarterly monitoring is the standard of care.

The longer answer involves understanding the mechanism of action at the receptor level, which I am happy to elaborate on if helpful.

21 22kim_atl_prep, sarah_TO, wendy_avl and 18 others
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Dr.RheumBOS
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Boston, MA
Jun 15, 2025 at 11:28 AM#23

Thank you hannah_MT! This is incredibly helpful. Bookmarking for later. 🙏

31 6cory_ATX, lori_vegas, Dr.PulmRoch and 28 others
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stefan_berlin
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Oct 2024
Berlin, DE
Jun 15, 2025 at 11:45 AM#24

Relevant to GGT as a liver health marker — here is my latest bloodwork comparison:

Key improvements: A1C 7.6% → 5.5%, triglycerides 209 → 109 mg/dL, hsCRP 8.0 → 0.9 mg/L. All on tirzepatide for 13 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

28 23TirzTom, TrialTracker_MD, JennaRN and 25 others
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JennaRN
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Colorado
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Jun 15, 2025 at 12:02 PM#25

Slightly tangential to GGT as a liver health but hannah_MT reminded me — what is the latest on the oral formulations?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

31 24SleepDoc_PDX, RegAffairsDC, BiostatsBrad and 28 others
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