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ForumsRetatrutide & Triple AgonistsPatient preference: weekly injection vs potential monthly depot — need advice Page 5

Patient preference: weekly injection vs potential monthly depot — need advice

BrianDallas92 Sat, Sep 20, 2025 at 3:44 AM 32 replies 1,267 viewsPage 5 of 7
Dr.SurgeonPGH
Senior Member
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Pittsburgh, PA
Sep 20, 2025 at 10:49 AM#21

Want to share my personal experience related to Patient preference weekly since I think it might help others in a similar situation.

I started my GLP-1 journey in March 2025 at 263 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.

Now, 10 months later: I am down 68 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The Patient preference aspect specifically was something that made a big difference in my journey.

This forum was my go-to resource throughout.

49 7DoseLogDan, SleepFixSam, PurityPaulOR and 46 others
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mike_mod
Moderator
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Sep 20, 2025 at 11:06 AM#22

Moderator note: Please keep vendor-specific discussions in the Vendor Reviews section.

I have cleaned up a few off-topic posts. 👍

Last edited: Sep 20, 2025 at 1:06 PM
33 18TomTeleRx, DoseLogDan, SleepFixSam and 30 others
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Dr.PeteFamMed
Senior Member
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Jan 2024
Minneapolis, MN
Sep 20, 2025 at 11:23 AM#23

Adding my data to this Patient preference weekly discussion:

MetricBaselineMonth 5Month 6
Weight240 lbs225 lbs215 lbs
A1C6.4%6.0%5.2%
hsCRP4.04.00.6

Protocol: Semaglutide 1.7mg/wk, resistance training 3x/wk, protein 1.2g/kg/day.

2 6LindaRN_retired, tommy_boulder
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VendorMark
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Sep 20, 2025 at 11:40 AM#24

nick_newbie — wow. This community is amazing.

41 14Dr.PeteFamMed, claudia_zurich, nancy_portland and 38 others
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SkepticalSean
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Jan 2025
Maine
Sep 20, 2025 at 11:57 AM#25
FDA_TrackerJim said:
Patient preference weekly is exactly what I've been researching

This is exactly right. FDA_TrackerJim articulated what I have been trying to explain to my friends for months. The Patient preference weekly aspect is what made the difference for me.

48 0Dr.LipidDallas, alex_tucson, kevin_tulsa and 45 others
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