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ForumsRetatrutide & Triple AgonistsTriple agonist side effect profile — what worked for you? Page 3

Triple agonist side effect profile — what worked for you?

Dr.BariatricHTX Sat, Aug 30, 2025 at 6:51 PM 12 replies 1,209 viewsPage 3 of 3
nick_newbie
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Aug 30, 2025 at 11:06 PM#11

ricardo_MIA — wow. This community is amazing.

39 12robert_kc, dan_philly, MeganSA_TX and 36 others
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sarah_TO
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Sep 2024
Toronto, CA
Aug 30, 2025 at 11:23 PM#12

Slightly tangential to Triple agonist side but Dr.BariatricHTX reminded me — what is the latest on the oral formulations?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

30 18Dr.EndoEP, GraceAZ_72, carl_compliance and 27 others
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james_edin
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Sep 2024
Edinburgh, UK
Aug 30, 2025 at 11:40 PM#13

Thanks for sharing this, Dr.BariatricHTX. A few questions about your Triple agonist side experience:

  1. What dose did you start at?
  2. How long before you noticed side effects improving?
  3. Did your provider have any specific recommendations about Triple agonist?

I am in a similar boat and trying to learn from others' experiences before my next appointment.

29 10tane_welly, Dr.PathRoch, mona_PHX and 26 others
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Dr.BariatricHTX
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Aug 30, 2025 at 11:57 PM#14

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Triple agonist side.

To answer sarah_TO: yes, I am on compounded sema from a 503B pharmacy.

Quick update: things are still going well. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

Last edited: Aug 31, 2025 at 5:57 AM
9 21stefan_berlin, Dr.EM_Chicago, pete_RVA and 6 others
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SleepDoc_PDX
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Portland, OR
Aug 31, 2025 at 12:14 AM#15

Relevant to Triple agonist side effect — here is my latest bloodwork comparison:

Key improvements: A1C 7.6% → 5.5%, triglycerides 229 → 99 mg/dL, hsCRP 8.0 → 1.1 mg/L. All on tirzepatide for 9 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

6 5mel_PDX, Dr.AddMedPHL, newstart_MO and 3 others
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