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ForumsRetatrutide & Triple AgonistsWill reta make sema and tirz obsolete? — my results so far Page 9

Will reta make sema and tirz obsolete? — my results so far

raj_cambridge Mon, Jun 23, 2025 at 10:58 PM 45 replies 1,803 viewsPage 9 of 9
pete_nash
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Nashville, TN
Jun 24, 2025 at 11:43 AM#41

Slightly tangential to Will reta make sema and but BenResearch_OR reminded me — what is the latest on the oral formulations?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

5 23Admin, Dr.Martinez, mike_mod and 2 others
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TrialTracker_MD
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Jan 2024
Maryland
Jun 24, 2025 at 12:00 PM#42

Relevant to Will reta make sema and tirz — here is my latest bloodwork comparison:

Key improvements: A1C 7.2% → 5.3%, triglycerides 207 → 107 mg/dL, hsCRP 6.0 → 1.3 mg/L. All on tirzepatide for 11 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

Last edited: Jun 24, 2025 at 5:00 PM
20 6stefan_berlin, Dr.EM_Chicago, pete_RVA and 17 others
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PharmHunterJen
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Jul 2024
Illinois
Jun 24, 2025 at 12:17 PM#43

Want to share my personal experience related to Will reta make sema and tirz since I think it might help others in a similar situation.

I started my GLP-1 journey in October 2024 at 248 lbs with prediabetes and hypertension. My endocrinologist prescribed semaglutide 0.25mg to start.

Now, 16 months later: I am down 68 lbs, my labs have normalized, and I am off 2 of my 3 medications. The Will reta make sema aspect specifically was something that made a big difference in my journey.

This community helped me every step of the way.

Last edited: Jun 24, 2025 at 6:17 PM
17 20kevin_tulsa, Dr.PainCLE, mike_mealprep and 14 others
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lucas_SP_BR
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Jun 2024
São Paulo, BR
Jun 24, 2025 at 12:34 PM#44

Relevant to Will reta make sema and tirz — here is my latest bloodwork comparison:

Key improvements: A1C 8.4% → 5.5%, triglycerides 209 → 109 mg/dL, hsCRP 8.0 → 0.9 mg/L. All on tirzepatide for 13 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

26 9KarenAZ_mom, zoe_NC, Dr.ObesityLA and 23 others
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MikeKY_noInsulin
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Oct 2024
Louisville, KY
Jun 24, 2025 at 12:51 PM#45

Want to share my personal experience related to Will reta make sema and tirz since I think it might help others in a similar situation.

I started my GLP-1 journey in March 2025 at 265 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.

Now, 8 months later: I am down 75 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The Will reta make sema aspect specifically was something that made a big difference in my journey.

This forum was my go-to resource throughout.

Last edited: Jun 24, 2025 at 3:51 PM
50 0bbq_ray_KC, oliver_london, tane_welly and 47 others
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