Following this thread closely. Retatrutide and blood is something I'm actively working through.

emily_PDX said:

I started my GLP-1 journey in March 2025 at 268 lbs with metabolic syndrome

Gonna push back on this one. Retatrutide and blood pressure is not that straightforward in my experience. I have been on this for 12 months and the reality is messier than the trials suggest.

Don't get me wrong — the medication works. But cost accessibility is a real barrier. We should be honest about that.

Want to share my personal experience related to Retatrutide and blood pressure since I think it might help others in a similar situation.

I started my GLP-1 journey in October 2024 at 274 lbs with prediabetes and hypertension. My endocrinologist prescribed semaglutide 0.25mg to start.

Now, 16 months later: I am down 84 lbs, my labs have normalized, and I am off 2 of my 3 medications. The Retatrutide and aspect specifically was something that made a big difference in my journey.

This community helped me every step of the way.

Saving this for reference. Top-tier content.

mike_nyc — that is really helpful context on Retatrutide and blood. Follow-up question: what labs did your doctor order to monitor this?

I am in a similar situation (just started) and trying to set realistic expectations.