Saving this for reference. Quality thread.

Slightly tangential to I was scared to order but JennaRN reminded me — has anyone else noticed changes in their alcohol tolerance?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

Relevant to I was scared to order from — here is my latest bloodwork comparison:

Key improvements: A1C 7.6% → 5.5%, triglycerides 209 → 109 mg/dL, hsCRP 8.0 → 0.9 mg/L. All on tirzepatide for 13 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

Want to share my personal experience related to I was scared to order from since I think it might help others in a similar situation.

I started my GLP-1 journey in March 2025 at 280 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.

Now, 8 months later: I am down 75 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The I was scared to aspect specifically was something that made a big difference in my journey.

This forum was my go-to resource throughout.

Dr.NateNeph — that is really helpful context on I was scared to order. Follow-up question: did you change anything about your diet at the same time?

I am in a similar situation (month 2) and trying to set realistic expectations.