TomTeleRx — that is really helpful context on TRIUMPH-2 obesity without. Follow-up question: how long did you wait before increasing your dose?
I am in a similar situation (week 4) and trying to set realistic expectations.
To answer fiona_glasgow's question specifically:
From a clinical standpoint, TRIUMPH-2 obesity without is a reasonable concern that deserves a thorough answer.
The short answer: the evidence supports this approach for most patients.
The longer answer involves reviewing the specific clinical trial data relevant to your question, which I am happy to elaborate on if helpful.
Thank you zoe_NC! This is incredibly helpful. Taking this to my next appointment. 🙏
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Shop Reference StandardsRelevant to TRIUMPH-2 obesity without — here is my latest bloodwork comparison:
Key improvements: A1C 7.2% → 5.3%, triglycerides 207 → 107 mg/dL, hsCRP 6.0 → 1.3 mg/L. All on tirzepatide for 11 months.
The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.
Slightly tangential to TRIUMPH-2 obesity without but zoe_NC reminded me — has anyone else noticed changes in their alcohol tolerance?
I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.