OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on A1C from 7.2 to 5.1 my.

To answer AttorneyGrant: yes, I am on compounded sema from a 503B pharmacy.

Quick update: things are still going well. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

Saving this for reference. Top-tier content.

Slightly tangential to A1C from 7.2 to 5.1 my but BenResearch_OR reminded me — what is the latest on the oral formulations?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

Relevant to A1C from 7.2 to 5.1 my — here is my latest bloodwork comparison:

Key improvements: A1C 7.2% → 5.3%, triglycerides 203 → 103 mg/dL, hsCRP 6.0 → 0.9 mg/L. All on tirzepatide for 7 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

Want to share my personal experience related to A1C from 7.2 to 5.1 my since I think it might help others in a similar situation.

I started my GLP-1 journey in October 2024 at 259 lbs with prediabetes and hypertension. My endocrinologist prescribed semaglutide 0.25mg to start.

Now, 14 months later: I am down 64 lbs, my labs have normalized, and I am off 2 of my 3 medications. The A1C from 7.2 to 5.1 aspect specifically was something that made a big difference in my journey.

This community helped me every step of the way.