PharmacoVig_BOS said:

24% weight loss number blew my mind is not that straightforward in my experience

This is exactly right. PharmacoVig_BOS articulated what I have been trying to explain to my friends for months. The 24% weight loss number aspect is what made the difference for me.

Reading this thread on 24% weight loss number hits close to home. Dad of 2 checking in — I started at 261 lbs and felt like I would tried everything.

7 months on tirz and I am a different person. Not just the 36 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about 24% weight loss — take the leap. It was the best health decision I have ever made. ❤️

julia.endo — that is really helpful context on 24% weight loss number. Follow-up question: how long did you wait before increasing your dose?

I am in a similar situation (week 4) and trying to set realistic expectations.

To answer pam_stl's question specifically:

From a clinical standpoint, 24% weight loss number blew my is a reasonable concern that deserves a thorough answer.

The short answer: the evidence supports this approach for most patients.

The longer answer involves reviewing the specific clinical trial data relevant to your question, which I am happy to elaborate on if helpful.

Bookmarked 📌 The 24% weight loss info in this thread is essential. Coming back to this for sure.