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Tagging this for the weekly digest. 👍

GraceAZ_72 — that is really helpful context on Insulin levels anyone. Follow-up question: did you change anything about your diet at the same time?

I am in a similar situation (month 2) and trying to set realistic expectations.

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Insulin levels anyone.

To answer SandraNC_45: yes, I am on compounded sema from a 503B pharmacy.

Quick update: things are still going well. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

GraceAZ_72 — that is really helpful context on Insulin levels anyone. Follow-up question: did you experience any side effects during this phase?

I am in a similar situation (about to start) and trying to set realistic expectations.

Want to share my personal experience related to Insulin levels anyone have since I think it might help others in a similar situation.

I started my GLP-1 journey in March 2025 at 284 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.

Now, 12 months later: I am down 39 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The Insulin levels aspect specifically was something that made a big difference in my journey.

This forum was my go-to resource throughout.