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Evidence-based GLP-1 & peptide discussion since 2023
ForumsLab Results & BiomarkersSHBG changes during weight loss on GLP-1 — need advice Page 4

SHBG changes during weight loss on GLP-1 — need advice

TirzTom Mon, Nov 13, 2023 at 2:05 AM 53 replies 3,010 viewsPage 4 of 11
JakeSmashed95
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Nov 13, 2023 at 7:45 AM#16

Congrats carl_compliance!! Keep going — you're doing incredible. 🎉

6 8Dr.PainCLE, mike_mealprep, NicoleRaleigh and 3 others
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BiostatsBrad
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Nov 13, 2023 at 8:02 AM#17

TirzTom's experience with SHBG changes during resonates deeply with mine. I went through almost the identical process — starting dose, titration timeline, side effects, everything.

The main difference: I had more GI issues initially. But the overall trajectory has been remarkably similar. Down 45 lbs in 10 months.

One thing I would add that TirzTom did not mention: insurance coverage was a major hurdle.

21 4Dr.BariatricHTX, LindaRN_retired, tommy_boulder and 18 others
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wanda_boise
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Nov 13, 2023 at 8:19 AM#18

Bookmarked 📌 The SHBG changes during info in this thread is essential. Coming back to this for sure.

Last edited: Nov 13, 2023 at 1:19 PM
18 7pam_columbus, nick_SD_fit, ben_calgary and 15 others
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newstart_MO
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Nov 13, 2023 at 8:36 AM#19

Clinical perspective on SHBG changes during weight loss on GLP-1:

I have managed over 200 patients on GLP-1 therapy and this topic comes up frequently. What the data shows — and what I see in practice — is that the medication works best as part of a comprehensive approach.

For this specific question, I would recommend: getting comprehensive baseline labs first.

Last edited: Nov 13, 2023 at 2:36 PM
38 7TrialNerd_Beth, HPLC_Greg, LibrarianMeg and 35 others
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stefan_berlin
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Nov 13, 2023 at 8:53 AM#20

Subscribing to this thread. SHBG changes during is exactly what I've been researching. 🙏

33 23TrialTracker_MD, JennaRN, LabKate and 30 others
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