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ForumsRetatrutide & Triple AgonistsRetatrutide Phase 2 dose-response analysis — need advice Page 3

Retatrutide Phase 2 dose-response analysis — need advice

SarahChen_PharmD Sun, Jun 16, 2024 at 8:40 PM 55 replies 2,123 viewsPage 3 of 11
SkepticalSean
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Maine
Jun 17, 2024 at 12:55 AM#11

Thank you Dr.SurgeonPGH! This is incredibly helpful. Taking this to my next appointment. 🙏

Last edited: Jun 17, 2024 at 4:55 AM
49 24DerekSJ_a1c, paige_pharma, emma_london and 46 others
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RickReta_CO
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Jan 2025
Colorado
Jun 17, 2024 at 1:12 AM#12

Slightly tangential to Retatrutide Phase 2 but SarahChen_PharmD reminded me — does anyone have experience combining this with metformin?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

19 5jim_asheville, matt_MKE, Dr.ReproEndo and 16 others
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NurseLeah_Nash
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Sep 2024
Nashville, TN
Jun 17, 2024 at 1:29 AM#13

Thanks for sharing this, SarahChen_PharmD. A few questions about your Retatrutide Phase 2 experience:

  1. What dose did you start at?
  2. How long before you noticed side effects improving?
  3. Did your provider have any specific recommendations about Retatrutide?

I am in a similar boat and trying to learn from others' experiences before my next appointment.

27 1PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 24 others
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SarahChen_PharmD
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San Diego, CA
Jun 17, 2024 at 1:46 AM#14

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Retatrutide Phase 2.

To answer RickReta_CO: I started tracking everything in a spreadsheet from day 1.

Quick update: I will post a proper update thread soon. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

48 2TinaHashiRN, robert_kc, dan_philly and 45 others
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Dr.PathRoch
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Jun 2024
Rochester, MN
Jun 17, 2024 at 2:03 AM#15

Adding my data to this Retatrutide Phase 2 discussion:

MetricBaselineMonth 3Month 8
Weight266 lbs236 lbs201 lbs
A1C7.0%5.8%5.4%
hsCRP5.02.00.8

Protocol: Semaglutide 2.4mg/wk, resistance training 3x/wk, protein 1.3g/kg/day.

Last edited: Jun 17, 2024 at 8:03 AM
15 12Dr.MetabolicMD, RetaRick_CA, JenPlateau and 12 others
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